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  • 1
    Digitale Medien
    Digitale Medien
    Comparative stability study of thymidine and (dideoxy-d-erythro-hexopyranosyl)thymine analogues monitored by capillary electrophoresis
    Amsterdam : Elsevier
    Journal of Chromatography A 687 (1994), S. 167-173 
    Details
    ISSN: 0021-9673
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    URL: http://linkinghub.elsevier.com/retrieve/pii/0021-9673(94)00764-0
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  • 2
    Digitale Medien
    Digitale Medien
    Dexamethasone associated systemic hypertension in low birth weight babies with chronic lung disease (1996)
    Springer
    European journal of pediatrics 155 (1996), S. 573-575 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Hypertension ; Dexamethasone ; Chronic lung disease
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract To assess the role of dexamethasone treatment as a cause of systemic hypertension and associated complications, blood pressure was registered prospectively before, during and after a 4-week dexamethasone course in 22 neonates with chronic lung disease. In all patients systolic blood pressure rose significantly during treatment (median rise 34 mm Hg, range 4→59 mm Hg), without complications attributable to hypertension. In all but one patient blood pressure returned to pretreatment values within 2 weeks after stopping dexamethasone treatment.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01957907
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  • 3
    Digitale Medien
    Digitale Medien
    Fetomaternal haemorrhage and prenatal intracranial bleeding: two more causes of blueberry muffin baby (1998)
    Springer
    European journal of pediatrics 157 (1998), S. 932-934 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Key words Blueberry muffin ; Fetomaternal haemorrhage ; Cutaneous haematopoiesis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Blueberry muffin lesions are associated with prenatal infections, severe and chronic anemia and neoplastic infiltrative diseases. In the first two instances they represent postnatal re-expression of cutaneous haematopoiesis, in the latter they are cutaneous localizations of a neoplastic disease. Chronic prenatal anaemia leading to blueberry muffin lesions in the neonate has been reported in association with severe haemolytic anaemia such as congenital spherocytosis, Rhesus haemolytic disease and ABO incompatibility, or in anaemia caused by twin-to-twin transfusion. We present two more causes of prenatal anaemia leading to blueberry muffin lesions: chronic fetomaternal haemorrhage and severe intracranial bleeding. Conclusion In any blueberry muffin baby with profound anaemia, chronic fetomaternal haemorrhage and severe internal bleeding should be included in the differential diagnosis. Skin biopsy must be performed to rule out neoplastic infiltrative diseases.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s004310050970
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  • 4
    Digitale Medien
    Digitale Medien
    Early prediction of chronic lung disease by tracheal aspirate cytology in ventilated newborns (1999)
    Springer
    European journal of pediatrics 158 (1999), S. 234-237 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Key words Squamous metaplasia ; Chronic lung disease ; Tracheal aspirate
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We assessed the specificity of squamous metaplasia in tracheal aspirates of 69 ventilated newborns (gestational age 25–41 weeks) between days 3 and 7 of life for prediction of chronic lung disease (CLD). CLD was diagnosed when the patient was still requiring ventilation or supplementary oxygen at the postconceptional age of 36 weeks (or postnatal age of 28 days for babies born after 32 weeks gestation) and showed X-ray changes compatible with CLD. In the total population the presence of squamous metaplasia had a sensitivity of 59% and a specificity of 74% for the early diagnosis of CLD. The combination of squamous metaplasia and very low birth weight (VLBW) had a much higher specificity (94%), but a lower sensitivity (45%). Our results show that the presence of sqaumous metaplasia in VLBW babies during the 1st week of life predicts development of CLD with a specificity of 94% and may be helpful for entering patients into early treatment protocols or trials when a high risk population needs to be identified. As sensitivity of this approach is only 45%, further studies are needed to evaluate the predictive value of the combination of cytology with other markers in tracheal aspirate specimens. Conclusion The presence of squamous metaplasia in tracheal aspirates of VLBW babies between days 3 and 7 of life is significantly associated with the development of chronic lung disease. Simple microscopic evaluation of fresh tracheal aspirates enables us to identify patients at high risk of CLD at a very early stage.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s004310051057
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  • 5
    Digitale Medien
    Digitale Medien
    Full triploidy in a liveborn preterm infant (1995)
    Springer
    European journal of pediatrics 154 (1995), S. 688-688 
    Details
    ISSN: 1432-1076
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02079083
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Dexamethasone associated systemic hypertension in low birth weight babies with chronic lung disease (1996)
    Springer
    European journal of pediatrics 155 (1996), S. 573-575 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Key words Hypertension ; Dexamethasone ; Chronic lung ; disease
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract To assess the role of dexamethasone treatment as a cause of systemic hypertension and associated complications, blood pressure was registered prospectively before, during and after a 4-week dexamethasone course in 22 neonates with chronic lung disease. In all patients systolic blood pressure rose significantly during treatment (median rise 34 mm Hg, range 4→59 mm Hg), without complications attributable to hypertension. In all but one patient blood pressure returned to pretreatment values within 2 weeks after stopping dexamethasone treatment. Conclusion Dexamethasone induced hypertension is transient, even after a 4-week course, and is not associated with hypertensive complications, so treatment is not necessary. When hypertension persists after dexamethasone withdrawal other causes should be considered.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01957907
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  • 7
    Digitale Medien
    Digitale Medien
    Collaborative study of the analysis of chlortetracycline by liquid chromatography on octylsilyl silica gel (1993)
    Springer
    Chromatographia 37 (1993), S. 640-644 
    Details
    ISSN: 1612-1112
    Schlagwort(e): Column liquid chromatography ; Chlortetracycline ; Reversed-phase silical gel ; C8 bonded phase ; Collaborative study
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Summary An established method for the analysis of chlortetracycline by liquid chromatography using octylsilylated silica gel as the stationary phase was examined in a multicentre study involving five laboratories and a total of six columns. Three chlortetracycline hydrochloride samples were analysed. The main component and the impurities were determined. An analysis of variance, treating each column as a different laboratory, showed an absence of consistent between-laboratory bias and the presence of a significant laboratory-sample interaction. The repeatability and the reproducibility of the method, expressed as relative standard deviations of the result of the determination of chlortetracycline hydrochloride, were calculated to be 0.9% and 1.1% respectively.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02274116
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