ZIB

Treffer pro Seite

Treffer 1 - 2 | 2 Treffer

Sortierung

Digitale Medien

The Influence of a Heparin-Coated Oxygenator During Cardiopulmonary Bypass on Postoperative Lung Oxygenation Capacity in Pediatric Patients with Congenital Heart Anomalies (1996)

Watanabe, Hiroshi ; Miyamura, Haruo ; Hayashi, Jun-ichi ; [weitere]

Oxford, UK : Blackwell Publishing Ltd

Journal of cardiac surgery 11 (1996), S. 0

zur Merkliste hinzufügen auf der Merkliste

Details

ISSN: 1540-8191

Quelle: Blackwell Publishing Journal Backfiles 1879-2005

Thema: Medizin

Notizen: Abstract Background: Cardiopulmonary bypass (CPB) causes an inflammatory response and remarkably depresses the oxygenation capacity of the lung in pediatric patients with pulmonary hypertension. Although a heparin-coated circuit is more biocompatible than an uncoated circuit, the beneficial effect of a heparin-coated circuit on the postoperative lung function in the pediatric patients remains unknown. Methods: Sixty patients younger than 3-years-old undergoing heart operations for ventricular septal defect were divided into three groups: group I = children (n = 11) without pulmonary hypertension who underwent CPB with an uncoated oxygenator; group II = children (n = 32) with pulmonary hypertension who underwent CPB with an uncoated oxygenator; and group III = children (n = 17) with pulmonary hypertension who underwent CPB with a heparin-coated oxygenator. A respiratory index (RI) was used to assess the oxygenation capacity of the lung. Results: RI in group II was significantly higher than in group I and intubation time in group II was significantly longer than in group I. There was a positive correlation between preoperative pulmonary-systemic blood pressure ratio and RI at 3 hours post-CPB. Three and six hours post-CPB, RI in group III was significantly lower than in group II, but there was no significant difference in RI between both groups at 12 hours post-CPB. Conclusions: Pulmonary hypertensive pediatric patients were vulnerable to postperfusion lung injury. Beneficial effects of a heparin-coated oxygenator in a CPB circuit was limited to the early hours post-CPB and the postoperative clinical course was not modified by the heparin-coating of a membrane oxygenator.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1111/j.1540-8191.1996.tb00070.x

Permalink

Bibliothek	Standort	Signatur	Band/Heft/Jahr	Verfügbarkeit

Andere fanden auch interessant ...

Artikel (Nationallizenzen)

Volltext

Digitale Medien

Placental transfer and effects of famotidine on neonates (1991)

Doi, Hisae ; Maruta, Hideo ; Kudoh, Ichidai ; [weitere]

Springer

Journal of anesthesia 5 (1991), S. 276-280

zur Merkliste hinzufügen auf der Merkliste

Details

ISSN: 1438-8359

Schlagwort(e): Famotidine ; Placental transfer ; Obstetric anesthesia

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract The effect of famotidine on neonates was studied in 34 obstetric patients who underwent elective cesarean section. In the famotidine group, 20 mg of famotidine was intramuscularly injected at 60 min before induction of anesthesia, and 0.5 mg of atropine was injected at 30 min before induction. In the control group, only atropine was given. Ratio of famotidine concentration in the umbilical venous blood to that in the maternal venous blood was determined as 0.64 ± 0.13 (mean ± SD). No significant differences were noted in the Apgar scores, neonatal gastric acidity, and results of liver function tests between the two groups. No side effect, such as the development of gastrointestinal infections, was observed. (Doi H, Murata H, Kudoh I, et al.: Placental transfer and effects of famotidine on neonates. J Anesth 5: 276–280, 1991)

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/s0054010050276

Permalink

Bibliothek	Standort	Signatur	Band/Heft/Jahr	Verfügbarkeit

Andere fanden auch interessant ...

Artikel (Nationallizenzen)

Volltext

Treffer 1 - 2 | 2 Treffer