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Digitale Medien

QT Dispersion in 120 Electrocardiographic Leads in Patients with Structural Heart Disease (2002)

STOVICEK, PETR ; GARDNER, MARTIN J. ; MITCHELL, L. BRENT ; [weitere]

Oxford, UK : Blackwell Futura Publishing, Inc.

Pacing and clinical electrophysiology 25 (2002), S. 0

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ISSN: 1540-8159

Quelle: Blackwell Publishing Journal Backfiles 1879-2005

Thema: Medizin

Notizen: STOVICEK, P., et al.: QT Dispersion in 120 Electrocardiographic Leads in Patients with Structural Heart Disease. The clinical significance of QT dispersion (QTd) measured in 12-lead ECGs is controversial. The aim of this study was to clarify factors that determine the QTd and its measurement errors in different lead arrays in patients with structural heart disease. Two blinded observers measured QT intervals on a computer screen from 120-channel ECG recordings in a retrospective set of 257 patients, comprising a group of 121 myocardial infarction (MI) survivors without ventricular tachyarrhythmia during a 6-month followup and a group of 136 survivors of ventricular tachyarrhythmia/fibrillation. QTd did not differ in patients with and without ventricular tachyarrhythmia/fibrillation. Eleven ventricular tachyarrhythmia/fibrillation survivors without structural heart disease had the lowest QTd (P ≤ 0.02). The strongest factor determining QTd and the magnitude of its measurement error was the lead array (P = 0.0001). Measurement errors had two components. The smallest relative errors were in the total body surface mapping array with one component related to interobserver reproducibility (9.1 ± 7.6%), and the other component related to accuracy of measurement of the QT interval (36 ± 16%). The authors estimated that a difference of QTd of at least 50 ms between study groups is required in a 12-lead ECG to draw any conclusions from the studies. In patients with structural heart disease, QTd from limited arrays of ECG leads was not a reliable measure. It correlated with the presence of structural heart disease, but not with arrhythmogenicity. An array consisting of ECG leads covering the entire chest allowed better reproducibility and measurement accuracy of QTd.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1046/j.1460-9592.2002.00020.x

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Digitale Medien

Trackways of Tetrapod Vertebrates from the Upper Devonian of Victoria, Australia (1972)

WARREN, JAMES W. ; WAKEFIELD, NORMAN A.

[s.l.] : Nature Publishing Group

Nature 238 (1972), S. 469-470

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ISSN: 1476-4687

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik

Notizen: [Auszug] The only previous report of pre-Carboniferous vertebrate trackways is the speculation by Willard3 that enigmatic marks on some Upper Devonian shales from Pennsylvania were caused by tetrapods, but this has never been verified or widely accepted. Thus, the Genoa River trackways are the earliest yet ...