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  • 1
    Electronic Resource
    Electronic Resource
    Allergy and atopic eczema I (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 6 (1981), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In recent years there has been an encouraging increase in interest in atopic eczema, particularly in relation to its immune logical aspects, and as a result there have been considerable advances in our understanding of the disease. Nevertheless, the relationship of the immunological derangements observed to the disease remains unclear. This relationship will be the principal subject of this review, which will be published in two parts. In the first, genetic and environmental factors predisposing to atopy and atopic eczema will be discussed, and the role of IgE and the significance of other phenomena in the pathogenesis of atopic eczema will then be considered. In the second part, the evidence that atopic eczema is an allergic disease, or more specifically, a food allergic disease, will be reviewed, and a model for the pathogenesis of eczema will be outlined.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.1981.tb02289.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A new teaching ‘laboratory’ for dermatology at Guy's Hospital (1977)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 2 (1977), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.1977.tb01554.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Laryngeal involvement in the Dowling–Meara variant of epidermolysis bullosa simplex with keratin mutations of severely disruptive potential (2000)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 142 (2000), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The clinical features of the Dowling–Meara variant of epidermolysis bullosa simplex (EBS-DM) can, in an infant, be indistinguishable from other severe forms of epidermolysis bullosa (EB). Two unrelated infants with no family history of skin disease are described who, within hours of birth, developed extensive blistering of skin and oral mucosae and who both subsequently developed hoarse cries. Despite this superficial resemblance to other forms of EB, electron microscopy revealed a basal cell rupture and keratin aggregates characteristic of EBS-DM in the skin of both infants and in the vocal cord epithelium of one. Molecular analysis confirmed the diagnosis by identification of mis-sense point mutations in basal cell keratin genes in both cases. One patient carries a point mutation in keratin 14 (converting arginine at position 125 to histidine) and the other has a novel point mutation in keratin 5 (converting serine at position 181 to proline). Hoarseness is not a well documented feature of EBS-DM and is usually associated with junctional EB. These two patients demonstrate that the presence of a hoarse cry in an infant affected by severe EB does not necessarily indicate a poor prognosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2000.03304.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Infantile gluteal granulomata—case report (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 9 (1984), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.1984.tb00849.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Neonatal lupus erythematosus (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 19 (1994), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We present a case of neonatal lupus erythematosus (NLE) in a black infant presenting with symmetrical depigmented macules on the face resembling vitiligo. NLE is a rare condition affecting newborn infants of mothers who have connective tissue disease, with or without autoantibodies to extractable nuclear antigens Ro (SS-A), La (SS-B) or ribonucleoproteins. Infants present with cutaneous lesions or congenital heart block or both. The skin lesions are usually annular and erythematous and transient and resemble those of subacute cutaneous lupus erythematosus. The presentation of this patient was therefore striking.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.1994.tb02695.x
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Angiosarcoma complicating xeroderma pigmentosum (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 21 (1992), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.1992.tb00370.x
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Gastrostomy and growth in dystrophic epidermolysis bullosa (1996)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 134 (1996), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary Chronic malnutrition and growth failure are features of severe dystrophic epidermolysis bullosa (DEB). Conventional dietetic interverion is of limited benefit. Oesophageal dilatation or reconstruction to alleviate stricture is associated with substantial risks. Surgical placement of a feeding gastrostomy is a comparatively straightforward procedure, provided that specialized anaesthetic and surgical techniques are employed. Gastrostomy insertion was undertaken in 18 children with severe DEB and the effects of this intervention were retrospectively evaluated. The majority received button devices (inserted primarily) and gastrostomy feeding supplemented oral intake. One year postoperatively, the average increase in weight standard deviation scores (SDS) of 13 patients was 0.9 SDS (9S% confidence interval 0.44. 1. 351 in Height 042 SDS (95% confidence interval 005, 0.79). One patient developed an incisional hernia and four patients experienced minor leakage around the gastrostomy entry site. Two patients never accepted their gastrostomies, which were therefore removed. Two further patients died for reasons unrelated to the procedure. Our observations suggest that gastrostomy feeding can play a valuable role in severe DEB and is associated with minimal morbidity. Such intervention is best undertaken before growth failure is established, and prior to puberty.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.1996.120855.x
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Histiocytosis X presenting as intertrigo and responding to topical nitrogen mustard (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 11 (1986), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This case serves as a reminder that intertrigo, which does not respond to conventional therapy, may be a presenting feature of histiocytosis X (HX). Topical nitrogen mustard therapy maybe useful in the treatment of cutaneous HX.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.1986.tb00445.x
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Hyper IgE syndrome—case history (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental dermatology 11 (1986), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The hyper IgE syndrome is a specific primary immunodeficiency disease of highly variable severity. Though the disorder is rare, patients are quite likely to present at some time to the dermatologist. Although the cutaneous manifestations of the hyper IgE syndrome are characteristic, they are non-specific and their significance may not be appreciated if a history of other infections, particularly of the respiratory tract, is not obtained.We describe here a typical case which presented in a paediatric dermatology clinic.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2230.1986.tb00482.x
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    (8) ? Scleredema of Buschke ? Eosinophilic fasciitis (1976)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 95 (1976), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1976.tb07902.x
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    Paper (German National Licenses)
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