ISSN:
1432-2072
Keywords:
Cannabis
;
Marihuana
;
Maze
;
Pre-Natal
;
Rats
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Pregnant Wistar MW-3 derived rats were treated with 250 mg/kg suboutaneously of an extract of Cannabis Sativa in 2.5 ml/kg of polyethylene glycol 300 or 2.5 ml/kg of polyethylene glycol 300 alone. A third group was left untreated. Treatments were made on days 8–11 of pregnancy. At term, the offspring were delivered normally by the mothers. Twenty-five offspring (15 males and 10 females) from each group were tested at 65 days of age in a Lashley III maze and were evaluated according to the following criteria: 3 out of 4 consecutive errorless trials; the number of errors committed and the time spent in the maze. The Cannabis Sativa treated group was significantly inferior to the polyethylene glycol group in all three parameters, although this difference was not demonstrated when evaluating females alone.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00439370
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