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  • 1
    Electronic Resource
    Electronic Resource
    Continence mechanism of the ileal neobladder in women: a urodynamics study (1998)
    Springer
    World journal of urology 16 (1998), S. 400-404 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We undertook this study to evaluate the mechanism of continence in women who underwent modified radical cystectomy and creation of an ileal neobladder. Our surgical technique was modified in accordance with detailed anatomic dissection of female pelvises with attention to the innervation of the pelvic musculature and urethral sphincter. Ten women aged 41–71 years (mean 64.3 years) underwent nerve-sparing radical cystectomy and creation of an orthotopic neobladder with detubularized ileum. Videourodynamic evaluation was performed 6 months postoperatively to evaluate sphincteric and reservoir function. Seven of the ten patients were totally continent after the procedure, requiring no protective pad. Of these, one requires intermittent self-catheterization. Videourodynamic evaluation revealed a low-pressure reservoir with a mean capacity of 467 ml, and leakage did not occur during Valsalva maneuver. Three patients reported significant incontinence (more than one pad per day) after orthotopic reconstruction. These patients demonstrated intrinsic sphincteric deficiency with a low mean abdominal leak-point pressure of 48.3 cmH2O. Two of these women had stress incontinence preoperatively. In conclusion, continence can be preserved in most women after modified radical cystectomy and orthotopic bladder replacement. Success results from preservation of the intrinsic sphincteric mechanism and the creation of a low-pressure, compliant reservoir. A history of stress incontinence preoperatively appears to predispose to sphincteric weakness postoperatively.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003450050090
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The rabbit as a model for neurourologic studies of the lower genitourinary tract (1990)
    Springer
    World journal of urology 8 (1990), S. 233-236 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We evaluated the rabbit as an animal model for the elucidation of the neurophysiology of erection, ejaculation, and bladder function. In 24 rabbits, stimulation of the hypogastric nerves resulted in penile tumescence and contraction of the seminal vesicles and vasa deferentia. Stimulation of the sympathetic trunks induced contraction of the penis, seminal vesicles, and vasa deferentia. Cavernous nerve stimulation induced penile erection with a mean intracavernous pressure of 113 cm H2O. Pelvic nerve stimulation elicited bladder contraction, but the intraluminal pressure was low (mean, 9.6 cm H2O) in comparison with that in other species. Our results indicate that the rabbit may be an appropriate, relatively inexpensive, and readily available model for the study of ejaculatory and erectile systems in man. However, because of anatomic variations, the rabbit bladder appears to be unsuitable for comparative studies in humans.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01580026
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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