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  • 1
    Electronic Resource
    Electronic Resource
    Further studies of scratching during sleep (1975)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 93 (1975), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Fifteen patients with a variety of itching skin diseases (atopic eczema, dermatitis herpetiformis, lichen planus, urticaria and psoriasis) have been studied in the sleep laboratory. Recordings were made of all-night electroencephalogram, electro-oculogram, submental electromyogram, and muscle potentials from both forearms.Bouts of scratching during orthodox (NREM) sleep occurred more frequently in stages 1 and 2 than in stages 3 and 4. The frequency in paradoxical (REM) sleep was close to that in stage 2 sleep. This pattern was similar for all the diseases studied and seems to be related to the physiology of the sleep stages rather than to the skin diseases themselves. The mean duration of the bouts of scratching was not related to the sleep stage in which they started.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1975.tb06495.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Effects of repeated ritanserin on middle-aged poor sleepers (1989)
    Springer
    Psychopharmacology 99 (1989), S. 219-221 
    Details
    ISSN: 1432-2072
    Keywords: Sleep ; 5HT2 antagonist ; Ritanserin ; Slow wave sleep ; Withdrawal
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Nine subjects who believed themselves to be poor sleepers, of mean age 58 years, took a placebo for 7 days, then ritanserin 5 mg for 20 days, followed by 3 days on placebo. Sleep was recorded electrophysiologically on 2 nights during baseline, 2 early drug nights, 2 late drug nights and the 2nd and 3rd withdrawal nights. Ratings of sleep quality were collected each morning. Ritanserin, a 5HT2 antagonist, caused a persistent doubling of the amount of EEG show wave sleep, without altering the total duration of sleep. Ritanserin decreased the frequencies of awakening and after about a week it appeared to improve the subjective quality of sleep. Sleep was then impaired during withdrawal, as indicated by decreased duration and poorer subjective quality, being worst on the 3rd withdrawal night.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442811
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Effects of loprazolam and of triazolam on psychological functions (1984)
    Springer
    Psychopharmacology 82 (1984), S. 386-388 
    Details
    ISSN: 1432-2072
    Keywords: Loprazolam ; Triazolam ; Residual effects ; Psychological functions ; Rebound insomnia ; Accidents ; Spontaneous complaints ; Manual dexterity ; Visual analogue scales
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Twelve poor sleepers of mean age 52 years performed 2 h of laboratory tests three times on 1 day during each week of nightly intake of loprazolam 0.5 mg, loprazolam 1 mg, triazolam 0.5 mg, or continued placebos. Only in the mornings did loprazolam 1 mg cause impairment in manual dexterity and card-sorting, and triazolam 0.5 mg in manual dexterity. Using difference from baseline, withdrawal of either drug after 3 weeks was associated with poorer subjective quality of sleep than following continuing placebos. The rate of spontaneous complaints (including accidents) associated with the drugs was as informative as formal testing.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00427691
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Effects of loprazolam and of triazolam on sleep and overnight urinary cortisol (1984)
    Springer
    Psychopharmacology 82 (1984), S. 389-394 
    Details
    ISSN: 1432-2072
    Keywords: Sleep ; Loprazolam ; Triazolam ; Tolerance ; Rebound ; Cortisol ; Noradrenaline
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Nine poor sleepers of mean age 61 years were studied while they took loprazolam 0.5 mg, loprazolam 1 mg and triazolam 0.5 mg for 3-week periods. Loprazolam 1 mg and triazolam 0.5 mg increased sleep duration, but there was some tolerance to both, particularly triazolam, by the 3rd week. Withdrawal of either drug led to sleep significantly shorter than baseline. This rebound effect was significant greater after withdrawing triazolam. After withdrawing loprazolam 1 mg, the rebound was maximal on the 3rd night and after withdrawing triazolam it was maximal and severe on the 1st night. In the third week of use neither drug was associated with late-night wakefulness. Total overnight urinary cortisol was lower during drug intake and there were significant withdrawal rebounds to above baseline levels, immediately so after triazolam.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00427692
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Viloxazine, sleep, and subjective feelings (1977)
    Springer
    Psychopharmacology 55 (1977), S. 121-128 
    Details
    ISSN: 1432-2072
    Keywords: Viloxazine ; Sleep ; Mood
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The sleep of eight volunteers (mean age 55) was recorded electrophysiologically while viloxazine 200mg was taken daily for 3 weeks, preceded and followed by a week of matching blanks. The volunteers also made ratings of their feelings on visual analogue scales. Another 15 volunteers (mean age 34) took viloxazine 300 mg daily for 3 weeks, preceded and followed by 3 weeks of matching blanks, and they also made daily ratings of feelings. The drug diminished sleep duration and caused more frequent and longer transitions into wakefulness and drowsiness. Slow-wave sleep decreased and stage 2 increased. REM sleep was markedly reduced, especially initially, and there was a withdrawal rebound. Viloxazine impaired subjective concentration, mood, and quality of sleep. Three volunteers, however, had striking mood elevation. The drug caused a small loss of weight, which correlated with gastrointestinal symptoms. Three older subjects experienced withdrawal vomiting and prostration. Viloxazine shares properties with imipramine and with amphetamines.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01457846
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Human body temperature is inversely correlated with body mass (1989)
    Springer
    European journal of applied physiology 58 (1989), S. 471-475 
    Details
    ISSN: 1439-6327
    Keywords: Human body temperature ; Body mass
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Forty-two women and 18 men of mean age 54 years had their sub-lingual oral temperature measured hourly from 0700 h to 2300 h. Mean oral temperature (averaged over the 17 readings) was inversely correlated with body mass in the group as a whole (r=−0.44,df=58,p=0.0003). The women had significantly higher mean oral temperatures than the men, but the inverse relationship between mean oral temperature and body mass was still significant when the data from the women were analyzed separately (r=−0.37,df=40,p=0.013). The results suggest that in humans, mean body temperature is inversely related to body mass, irrespective of gender.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02330699
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    Paper (German National Licenses)
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