ISSN:
1434-4726
Keywords:
Key words Angiocentric B cell lymphoma
;
Temporal bone neoplasms
;
Otitis media
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Involvement of the temporal bone in patients with malignant lymphomas is very rare. Most of the reported cases have been clinically asymptomatic and were diagnosed only by post-mortem examinations. We present a nasal, paranasal, nasopharyngeal lymphoma that occurred in a 12-year-old child and also involved the temporal bone. Clinical presentation began with bilateral chronic otitis media. Histopathologically, tumor was found to be an angiocentric lymphoma of B-cell origin. Association with Epstein-Barr virus could not be demonstrated. Despite combination chemotherapy (with cyclophosphamide, vincristine, doksorubicine, prednisolone, l-asparaginase, cytosine arabinoside, metotraxate) and radiotherapy (to 40 Gy), disease progressed locally as well as to cervical lymph nodes and the lungs.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004050050154
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