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  • 1
    Electronic Resource
    Electronic Resource
    Development of a small RGD peptide fibrinogen receptor antagonist with potent antiaggregatory activity in vitro (1991)
    s.l. : American Chemical Society
    Journal of medicinal chemistry 34 (1991), S. 3114-3125 
    Details
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jm00114a022
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  • 2
    Electronic Resource
    Electronic Resource
    On Comparing Alternative Advertising Policies of Pulsation (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Decision sciences 23 (1992), S. 0 
    Details
    ISSN: 1540-5915
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: In this paper, five alternative advertising policies that belong to the advertising pulsation class are compared analytically for linear and concave response functions using a modified version of the Vidale-Wolfe model. The results of the research show that (1) For both linear and concave response functions, advertising pulsing/maintenance policy dominates advertising pulsing policy but is dominated by the Uniform Advertising Policy. For convex response functions, the order of dominance is reversed. (2) For linear response functions, uniform advertising policy dominates the impulse advertising policy but is dominated by the chattering advertising policy. (3) For concave response functions, uniform advertising policy dominates both the impulse advertising policy and the chattering advertising policy. (4) For convex response functions, chattering advertising policy dominates both the advertising pulsing policy and the impulse advertising policy.The Vidale-Wolfe model is estimated using the well-known Lydia Pinkham data. Optimality analysis shows that the company was overadvertising about half of the time studied. Overadvertising seems to have produced appreciable gain in sales and created significant barriers to competitive entry at a little cost in terms of foregone profits.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-5915.1992.tb00405.x
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  • 3
    Electronic Resource
    Electronic Resource
    Basal Cell Carcinoma With Matrical Differentiation in a Transplant Patient: A Case Report and Review of the Literature (2005)
    Oxford, UK; Malden, USA : Blackwell Publishing Ltd/Inc.
    Journal of cutaneous pathology 32 (2005), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: Shadow cells are characteristic of pilomatricoma, a distinct neoplasm of hair matrix differentiation. Shadow cells within an otherwise classic basal cell carcinoma (BCC) has been referred to as “BCC with matrical differentiation”. We present a case of BCC with matrical differentiation in a transplant patient. To our knowledge, none have been reported arising on the background of immunosuppression. Methods: A 58-year-old male cardiac transplant patient had a left hand nodule, which was excised and submitted for routine histologic review. Results: The lesion revealed multiple basaloid tumor masses. In some areas, there was peripheral palisading with stromal retraction artifact, typical of basal cell carcinoma, extending into the deep reticular dermis. The tumor also contained a population of shadow cells, similar to those in pilomatricoma, with basaloid cells in the periphery. Trichohyaline granules were identified in many of the tumor cells. These granules are a hallmark of follicular matrix differentiation. Mitoses were rare. There was no evidence of an infiltrating growth pattern. Conclusion: Basal cell carcinoma with matrical differentiation is a rare subtype of basal cell carcinoma featuring shadow cells, such as those typically seen in pilomatricoma. This tumor has not yet been reported in an immunosuppressed transplant patient.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0303-6987.2005.0320f.x
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  • 4
    Electronic Resource
    Electronic Resource
    Asthma and allergic diseases in schoolchildren: third cross-sectional survey in the same primary school in Ankara, Turkey (2004)
    Oxford, UK : Munksgaard International Publishers
    Pediatric allergy and immunology 15 (2004), S. 0 
    Details
    ISSN: 1399-3038
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We investigated prevalence and determinants of asthma and allergic diseases in a cross-sectional survey of schoolchildren aged 6–14 in 2002. This was the third of a series of cross-sectional surveys, conducted in 1992 and 1997, in the same school in Ankara, Turkey. Questionnaire including information on house characteristics, dietary habits, past and current exposures and diseases were distributed to 1064 children (523 boys, 541 girls) and filled by the parents at home. Percentage of children having a pet was significantly higher (1992: 7.9, 1997: 22.9, 2002: 21), but that of passive smoking was significantly lower (1992: 74, 1997: 64, 2002: 64.1) in 1997 and 2002 when compared with 1992. Current prevalence percentage of asthma (1992: 8.3, 1997: 9.8, 2002: 6.4), wheeze (1992: 11.9, 1997: 13.3, 2002: 6.4), hay fever (1992: 15.4, 1997: 14.1, 2002: 7.2), and eczema (1992: 4, 1997: 4.3, 2002: 1.8) were significantly lower in 2002 compared with 1992. Multiple logistic regression analysis model for current wheeze included ingestion of cow's milk (no regular ingestion: reference, ORs and 95% CIs, 〈1 glass/day: 0.5, 0.3–1.0; at least 1 glass/day: 0.3, 0.2–0.7), ingestion of red meat (2.2, 1.2–3.8), and currently holding a dog (6.1, 1.6–23.4). Multiple logistic regression analysis model for current hay fever included ingestion of red meat (1.8, 1.1–2.9) and father's education (none of the parents finished secondary school: reference, secondary school to university: 0.5, 0.2–1.0). Our findings suggested that current prevalence of asthma and allergic diseases decreased among schoolchildren in Ankara, in the last 10 yr, and ingestion of milk and red meat could have a role in the occurrence of asthma and hay fever. Detailed assessment of dietary habits is required to test this hypothesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1399-3038.2004.00202.x
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  • 5
    Electronic Resource
    Electronic Resource
    Metabolic characteristics of the Japanese clam Ruditapes philippinarum (Adams & Reeve) during aerial exposure (2000)
    Oxford, UK : Blackwell Science Ltd
    Aquaculture research 31 (2000), S. 0 
    Details
    ISSN: 1365-2109
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Some metabolic end-products in tissues and physiological parameters of haemolymph of the Japanese clam Ruditapes philippinarum (Adams & Reeve) were investigated under aerial exposure at 15 °C with low relative humidity (RH) (22%) or high RH (91%). Acclimated clams in water at 15 °C were used as a control and to supply the low or high RH experiment. The low RH experiment was conducted at air exposure for 50 h (LH50), and the high RH experiment for 50 h (HH50) and 100 h (HH100). Accumulation of succinate and alanine in the tissues proved that the clam shifted its metabolism to anaerobiosis. Lactate accumulation did not occur. Glucose concentrations in tissues increased slightly during exposure except for HH50. The total free amino acid contents (363–410 μmol g−1) were higher than those of glucose (530–804 μmol 100 g−1), suggesting that the free amino acids might play a more dominant role in the metabolism. Increase in the haemolymph pco2 did not influence the acid–base balance in the haemolymph during exposure at both humidity conditions. Increase in the haemolymph ammonia from 48.2 to 57.1 μmol 100 g−1 and to 131.0 μmol 100 g−1 at LH50 and HH100, respectively, suggested that ammonia might function as an important buffering factor during aerial exposure. Retention values of the haemolymph po2 even at the longest exposure time (16.30 mmHg at LH50 and 14.69 mmHg at HH100) indicated that the clams depend partially on some aerobic manner.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2109.2000.00402.x
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  • 6
    Electronic Resource
    Electronic Resource
    Effect of temperature and relative humidity on the tolerance of the Japanese clam, Ruditapes philippinarum (Adams & Reeve), to air exposure (1999)
    Oxford, UK : Blackwell Science Ltd
    Aquaculture research 30 (1999), S. 0 
    Details
    ISSN: 1365-2109
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Laboratory studies showed that higher relative humidity (RH) and lower air temperature increase the tolerance of the Japanese clam, Ruditapes philippinarum (Adams & Reeve), to exposure. Aerial respiration of the clam was also measured. At high RH, the exposure time which gave 50% survival (LT50) was 1.97 and 1.75 times longer than in low RH at air temperatures of 15 and 25 °C, respectively. At 15 °C, all clams previously acclimatized at 15 °C survived for 58 h at low RH and 102 h at high RH. These differences can potentially be exploited to improve the shipment of clams. The aerial respiration experiment showed that the increase of the oxygen consumption rate at 25 °C was greater than that at 15 °C, following an increase in exposure time. The aerial respiration rates of the clams were ≈ 41.6% and 50.0% of those in water at 25 and 15 °C, respectively. The survival of the clams in air was dependent on aerobic rather than anaerobic respiration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2109.1999.00303.x
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  • 7
    Electronic Resource
    Electronic Resource
    An analysis of the virtual value chain in electronic commerce (2001)
    Bradford : Emerald
    Logistics information management 14 (2001), S. 78-85 
    Details
    ISSN: 0957-6053
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: In electronic commerce, businesses require to integrate two kinds of activities - ones that are embedded into the physical value chains and the others that are built through information into the virtual chain. Although the relative importance of these two kinds of chain depends on the characteristics of the products and services, their integration, nevertheless, plays a critical role in the success of e-commerce. In e-commerce, more and more value chain activities are conducted electronically, therefore, businesses should understand the implication of the virtual value chain activities. The virtual chain offers a number of distinct advantages over the physical value chain. Some of these advantages lie in forging alliances between customers and manufacturers, advertising products and services selectively with effects of audio, video, and graphics, and saving time and money in efficiently processing customer orders and enquiries. Besides, e-commerce offers flexibility in option pricing and customization of products and service, by reducing the constraints of time and space.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/09576050110362465
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  • 8
    Electronic Resource
    Electronic Resource
    Temperature and Light Requirements for the Sprouting of Chilled and Unchilled Tubers of the Purple Nutsedge, Cyperus rotundus (1978)
    Oxford, UK : Blackwell Publishing Ltd
    Physiologia plantarum 44 (1978), S. 0 
    Details
    ISSN: 1399-3054
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Mature and immature tubers of purple nutsedge (Cyperus rotundus L.) chilled at 0°C in dry and wet conditions, were sprouted along with fresh, unchilled tubers over a range of temperatures (10°C-45°C) in light and darkness. Fresh immature tubers showed a high sprouting percentage at all temperatures between 20°C and 40°C, while the mature ones did so only at 30°C and 35°C. Chilling of dry tubers stimulated early sprouting and increased the maximum sprouting percentage of both the mature and immature tubers. Dry chilling also lowered the limit of favourable temperatures to 15°C in the case of mature tubers. Chilling of wet tubers had a depressing effect and no sprouting occurred below 30°C.At all temperatures, light apparently favoured the sprouting of both the mature and immature tubers (except mature wet-chilled ones at 35°C and 40°C). Immature tubers showed relatively higher sprouting percentage than the mature ones, both in light and darkness. Alteration of temperature requirements due to dry and wet chilling of the tubers is regarded as significant and functional in relation to the ecology of the species.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1399-3054.1978.tb08617.x
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  • 9
    Electronic Resource
    Electronic Resource
    Simplified method of estimating masticatory performance (1999)
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 26 (1999), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Methods which measure masticatory performance include gravimetric, volumetric and direct observation which depend on the weight, volume and size, respectively, of a test food once chewing is completed. Almonds, one of the most common test foods used, have a convenient size and texture. However, due to their oily content and mixing with saliva, washing and drying is required to overcome the clumping of chewed particles. A method has been developed using bagged almonds to exclude saliva and preventing loss of almond particles in the mouth. In addition, microwaving the whole almond reduces the oil content of the almond, reducing clumping, and potentially eliminating the need for washing and drying the particles. A dentate volunteer was asked to chew seven blanched almonds and seven microwaved almonds. The chewed particles were separated using two sieves, weighed and optically scanned to measure the number and area of the particles. Results were obtained both before and after washing and drying of the chewed particles. The overall results for the test of masticatory performance is very similar whether or not a washing stage is used for microwaved almonds. For untreated almonds washing has a more noticeable effect and may still be considered necessary.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2842.1999.00429.x
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  • 10
    Electronic Resource
    Electronic Resource
    Interdependence and Volatility Spillovers Under Market Liberalization: The Case of Istanbul Stock Exchange (2003)
    Oxford, UK : Blackwell Science Ltd
    Journal of business finance & accounting 30 (2003), S. 0 
    Details
    ISSN: 1468-5957
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: This paper analyzes stock returns and volatility relations between the Istanbul Stock Exchange (ISE) and the global market as represented by stock markets in the US, the UK, Japan and Germany. Results from monthly data and multivariate cointegration tests suggest that the ISE became significantly integrated in the global market only in the period following market liberalization in late 1989. We also find evidence based on GARCH estimations that capital liberalization actually mitigated, rather than intensified, volatility in the ISE. Our results further suggest that the Asian crisis in mid-1997 and the consequent Russian economic meltdown in mid-1998 are partly responsible for the recent excessive volatility in the Turkish market. The results also identify the US and the UK markets as dominate sources of volatility spillovers for the ISE, even in the period following the Asian-Russian crises. Consequently, it appears that the two matured markets of the US and the UK shoulder significant responsibility for the stability and financial health of smaller emerging markets like the ISE.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/1468-5957.05499
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