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  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 222 (1969), S. 1278-1279 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Bone marrow when cultured in vitro sooner or later gives rise to cells which resemble fibroblasts. We have cultured marrow from patients with chronic granulocytic leukaemia, but chromosomal analysis of the resulting fibroblasts failed to reveal the Ph1 chromosome. Marrow was obtained from seven ...
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Wir berichten über einen postpneumonischen Lungenabszeß bei einem 18 Monate alten Mädchen. Während der bakteriämischen Phase der Erkrankung war im Urin der Patientin mit Gegenstromelektrophorese eine Präzipitationslinie mit Pneumokokken-Antiserum nachzuweisen. Nachdem im späteren Verlauf der Erkrankung ein Lungenabszeß diagnostiziert worden war, fand sich im Abszeßeiter eine positive Reaktion mit omnivalentem Pneumokokken-Serum und mit Pneumokokken Typ 3-Antiserum. In diesem Krankheitsstadium war der Eiter steril, Blutkulturen waren negativ. Der Fall zeigt, daß die Gegenstromelektrophorese ein einfaches Verfahren für eine rasche und bis hin zum Serotyp exakte Diagnose darstellt.
    Notes: Summary We are reporting the case of an 18-month-old girl with a post-pneumonic lung abscess. The counterimmunoelectrophoresis (CIE) of the patient's urine during the bacteremic phase of the disease gave a precipitation line with pneumococcal antiserum. Later in the course of the disease, after the diagnosis of lung abscess had been established, the pus drained from the abscess gave positive reactions with pneumococcal omnivalent serum and type 3 pneumococcal antiserum. At this stage, the pus was sterile and blood cultures were negative. This case demonstrates that the CIE test is a simple procedure which gives a rapid and exact diagnosis up to the serotype level.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The repair of hemopoietic bone marrow following evacuation of the tibial or femoral cavity of the rat was sequentially studied with the light microscope. A stereotyped train of histologic events occurred. These were capillary invasion of the cavity, appearance of primitive mesenchymal cells, osteoblastic proliferation, cancellous bone formation, development of sinusoids, reappearance of hemopoietic tissue and resorption of cancellous bone. The studies suggest that restoration of marrow sinusoids takes place only in the interstices of cancellous bone. Mechanical disruption of the sinusoidal system is one method of triggering cancellous bone formation. The cancellous bone which appeared after injury was thought to be produced by endosteal osteoblasts and osteoblasts derived from cells residing in normal hemopoietic tissue. Localized radiation of the tibia followed by mechanical disruption of hemopoietic tissue demonstrated that cancellous bone production and the repair process were unimpaired by 1,000 r but were completely blocked by 4,000 r. This would imply that the cell which can differentiate into an osteoblast is resistant to 1,000 r.
    Type of Medium: Electronic Resource
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