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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Documenta ophthalmologica 90 (1995), S. 143-155 
    ISSN: 1573-2622
    Keywords: Electroretinogram ; Fourier analysis ; Naka-Rushton equation ; Obesity surgical therapy ; Oscillatory potentials ; Vitamin A deficiency
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract New possible causes and unexplored aspects of the electroretinogram were evaluated in a case of vitamin A deficiency secondary to surgical therapy for morbid obesity. The Naka-Rushton equation, applied to the scotopic b-wave, demonstrated the quantal catch reduction caused by the loss of rhodopsin in the outer segment of photoreceptors. Study of the Fourier analysis of the photopic 20-Hz response suggested a primary involvement of the external retinal layers, with an indirect alteration of the inner layer. The electroretinogram oscillatory potentials showed alterations explained by the involvement of their generators related to the primary photoreceptor lesion.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-2622
    Keywords: electroretinogram ; oscillatory potentials ; retinitis pigmentosa
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The alterations of the inner retina in retinitis pigmentosa have been described in previous papers less often than the external retina alterations, both from the electrophysio-logical and morphological point of view. The oscillatory potentials (OPs) of the electroretinogram (ERG) are a good tool to investigate the inner part of the retina because of the deep anatomical location of their generators. We studied the photopic OPs in a group of 25 subjects affected with retinitis pigmentosa and compared them with other ERG components to obtain information about the functional damage of the inner retina. The OPs were recordable in 9 patients. No analogies were found with the inheritance modes. No relationship was found between OPs and 20 Hz ERG photopic response which was still present in a consistent number of eyes when OPs were no longer recordable. Such finding can be interpreted as an expression of inner retinal damage paralleling the photoreceptors and retinal pigment epithelium impairment.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Graefe's archive for clinical and experimental ophthalmology 227 (1989), S. 131-135 
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Wolfram, or DIDMOAD, syndrome is a genetic disorder characterized by diabetes insipidus, diabetes mellitus, optic atrophy and deafness. We studied a family in which only diabetes mellitus and primary optic atrophy were present in three female siblings. Two of these patients, fraternal twins, were subjected to a complete electrophysiologic examination. The possibility of an incomplete clinical expression of Wolfram syndrome, hypotheses of its genetic transmission, and diagnostic problems are discussed.
    Type of Medium: Electronic Resource
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