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  • 1
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Twenty-one mild asthmatic patients allergic to cat dander underwent a bronchial provocation test (BPT) with a cat extract. An early allergic response (EAR) was observed in all 21 patients and a late allergic response (LAR) in 8/21 patients. In the EAR, the patients with subsequent LAR had a greater full in FEV1, Their baseline FEV1, and total dose of inhaled allergen were not significantly different from patients who did not develop a LAR, but their serum specific IgE level was higher. Crossed immunoelectrophoresis (CIE) of the same cal extract showed that it contained eight different proteins. An IgE-CRIE was obtained from all 21 patients, using radiolabelled anti-lgE and autoradiography. Radiolabelled standards allowed a semiquantitative scoring of the radiosiaining. The CRIE pattern of the eight patients with LAR showed a higher score of radiostaining and a greater number of proteins hound to IgE. The two major allergen cal albumin and Fel d I bound equally to IgE of patients with and without LAR whereas another protein (antigen No. 7) bound to IgE of 100% of patients with LAR but of only 38% of patients without LAR. These data suggest that the pattern of the IgE response to specific proteins of a cat extract may be related to the occurrence of LAR after BPT with this allergen.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The Pharmacia CAP system is a new assay for specific IgE characterized by a new solid phase (hydrophilic polymer encased in a capsule). The CAP results were compared to those of the Phadebas IgE RAST and skin-prick tests (SPT) performed in 145 subjects suffering from rhinitis and/or asthma with eight common inhalant allergens (total number of tests = 1160), Concording CAP/RAST results were found in 91% of the tests The CAP was positive in 78% and the RAST in 65% of the positive SPT. Conversely, the CAP was negative in 90.6% and the RAST in 96.4% of the negative SPT. A pattern ‘negative SPT, negative RAST and positive CAP’ was found in 56 tests (41) subjects): in four such subjects, the CAP posilivity was confirmed by a positive IgE crossed radio-immunoclcctrophoresis. Three borderline positive results were found among 240 negative controls (serum from cord blood or non-atopies). These data indicate that compared with SPT the CAP system is (a) more sensitive than the Pharmacia RAST and (b) does not seem less specific.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 255 (1994), S. S335 
    ISSN: 1432-0711
    Keywords: Coeliochirurgie ; fibrome utérins ; myomectomie ; hystérectomie ; Operative laparoscopy ; uterine myomas ; myomectomy ; hysterectomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Only complicated fibromas refractory to medical treatment should be treated surgically. Two types of operations can be proposed for interstitial and subserosal fibromas: myomectomy and hysterectomy. The indication, based on a through preoperative assessment, depends on the patient's age and the size, number and sites of the fibromas and associated lesions. Preliminary series confirm the feasibility of these two operations performed by laparoscopy, as a result of the progress in this modality over recent years. In the future, larger series will determine the respective place of each of these surgical procedures in relation to others surgical possibilities.
    Notes: Résumé Seuls les fibromes compliqués et/ou résistants aux traitements médicaux relèvent de la chirurgie. Deux types d'interventions peuvent être proposées pour les myomes interstitiels et sous séreux: la myomectomie et l'hystérectomie. L'indication, posée après un bilan pré-opératoire soigneux, dépend de l'âge de la patiente, de la taille, du nombre et de la localisation des myomes ainsi que des lésions associées. Les progrès réalisés ces dernières années en matière de coeliochirurgie permettent, à partir de séries préliminaires, de pouvoir affirmer la faisabilité de ces deux interventions par voie coelioscopique. Les années à venir permettront, à partir de séries plus importantes de patientes, de préciser la place respective de chacune de ces interventions par rapport aux autres possibilités chirurgicales.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-2277
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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