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  • 1
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    "Greatness Engendered: George Eliot and Virginia Woolf", by Alison Booth (Book Review) (1993)
    Bloomington, Ind. : Periodicals Archive Online (PAO)
    Victorian Studies. 37:1 (1993:Autumn) 158 
    Details
    ISSN: 0042-5222
    Topics: English, American Studies , History
    Notes: BOOK REVIEWS
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:6262-1993-037-01-000020
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  • 2
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    Hardy's Laodicean Narrative (1989)
    Baltimore, Md. : Periodicals Archive Online (PAO)
    Modern fiction studies. 35:2 (1989:Summer) 211 
    Details
    ISSN: 0026-7724
    Topics: Linguistics and Literary Studies
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:5040-1989-035-02-000002
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  • 3
    Electronic Resource
    Electronic Resource
    James Thomson and the Continuum of Labor (1992)
    New York : Cambridge University Press
    Victorian literature and culture 20 (1992), S. 69-98 
    Details
    ISSN: 1060-1503
    Source: Cambridge Journals Digital Archives
    Topics: English, American Studies , History
    Notes: When in 1876 James Thomson asked readers of the Secularist, “Why work, work, work..., ” he recalled the futile asceticism of Carlyle's biblical command, for to the younger man, the Night (in Sartor Resartus) that awaited all laborers seemed “black[,] abyssmal... inscrutable, utterly void and silent” (Essays 144). Unsupported by doctrinal faith in God or an afterlife, the Carlylean imperative was in fact, Thomson tells his readers in “Indolence,” a command to “save yourselves from yourselves; to overwhelm and exhaust the natural... man in each of you; to occupy all your hours and make them pass as swiftly as possible, thus distracting yourselves from vain talk and thought and self-consciousness, until you are... impotent for further mischief” (144).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1017/S106015030000512X
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  • 4
    Electronic Resource
    Electronic Resource
    Cranial irradiation after surgical excision of brain metastases in melanoma patients (1996)
    Springer
    Annals of surgical oncology 3 (1996), S. 118-123 
    Details
    ISSN: 1534-4681
    Keywords: Melanoma ; Brain metastasis ; Radiation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Brain metastases account for 20–54% of reported deaths from melanoma. Duration and quality of survival depend on the extent of metastatic disease and response to treatment. Treatment goals are palliation of symptoms and prolongation of life. No studies have directly compared surgery alone and surgery with adjunctive cranial irradiation in patients with solitary brain metastases. Methods: We evaluated postoperative adjunctive cranial irradiation in 34 patients with solitary brain metastases. Results: Overall survival was significantly improved in the 22 patients who received adjunctive cranial irradiation versus that in the 12 patients who had surgery alone. Twenty-eight patients subsequently relapsed. Nine of 10 patients with surgery alone had brain recurrence as a component of failure. Six of 10 patients not receiving irradiation had brain recurrences as a component of relapse at multiple sites whereas only 1 of 18 patients receiving irradiation relapsed with the brain. Conclusions: Adjunctive cranial irradiation is justified for melanoma patients who undergo surgical therapy for solitary brain metastases. Survival in patients presenting with solitary brain metastases was improved by a reduction of relapse in the brain as a component of failure by combined surgery and irradiation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02305789
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  • 5
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    Reading and the Romantics: Ruskin's "Fiction Fair and Foul" (1990)
    Boston, Mass. : Periodicals Archive Online (PAO)
    Studies in Romanticism. 29:4 (1990:Winter) 583 
    Details
    ISSN: 0039-3762
    Topics: Linguistics and Literary Studies
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:b321-1990-029-04-000004
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  • 6
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    Painterly Perspective and Authority in Victorian Writings (1989)
    Winnipeg, Man. : Periodicals Archive Online (PAO)
    Mosaic. 22:4 (1989:Fall) 71 
    Details
    ISSN: 0027-1276
    Topics: Linguistics and Literary Studies
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:h155-1989-022-04-000006
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  • 7
    Electronic Resource
    Electronic Resource
    Immunoelectron microscopic localization of HLA-DR antigen in control small intestine and colon and in inflammatory bowel disease (1986)
    Springer
    Digestive diseases and sciences 31 (1986), S. 1317-1330 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have elucidated the distribution of I2 (HLA-DR) antigen in control and inflammatory bowel disease specimens, using immunoelectron microscopic methods. Control small intestinal epithelium and inflammatory bowel disease epithelium expressed I2 antigen, while control colonic epithelium did not. I2 expression by enterocytes was more frequent on the lateral and basal surface than on the microvillus surface. Two of three M cells in control ileum expressed I2 antigen. I2-positive intraepithelial lymphocytes were rarely detected in both control and disease specimens. I2-positive lamina propria lymphocytes were significantly increased in inflammatory bowel disease, while I2-positive lamina propria lymphocytes were virtually absent in control specimens. I2-positive mononuclear cells in the intestinal lamina propria were largely macrophages and monocytes in both control and inflammatory bowel disease specimens. I2-positive mononuclear cells resembling dendritic cells were not detected in control or disease specimens. Furthermore, there were no significant morphological differences in I2-positive or-negative macrophages and monocytes in control and disease specimens. The expression of I2 antigen on Schwann cells was detected more frequently in disease specimens than in control specimens. Capillary endothelia of both control and disease specimens expressed I2 antigen. We demonstrate that I2 expression is present on surface membranes of both immune and nonimmune cells of the intestine and colon and show that this expression is more prominent in inflammatory bowel disease than in control intestine and colon. Further studies are required to determine whether this finding is meaningful in terms of antigen presentation and whether this apparent “immune activation” is involved in the pathogenesis of inflammatory bowel disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01299810
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  • 8
    Electronic Resource
    Electronic Resource
    Immunohistological characterization of intraepithelial and lamina propria lymphocytes in control ileum and colon and in inflammatory bowel disease (1986)
    Springer
    Digestive diseases and sciences 31 (1986), S. 593-603 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Using monoclonal antibodies to T and B lymphocytes, to natural killer cells, and to HLA-DR antigen, we characterized the lymphocyte population within the epithelial and lamina propria regions in control intestine and colon, and in grossly involved and in grossly uninvolved intestine and colon of patients with active inflammatory bowel disease. There were significantly more intraepithelial T cells in control ileum than in control colon. In comparison to control, there was a heterogeneity of alterations in intraepithelial and lamina propria T lymphocyte subsets (T11+, T8+, T4+) in inflammatory bowel disease. B lymphocytes were not detected within the lamina propria, except when found in and adjacent to lymphoid aggregates. Leu 7+ cells were uncommon in the lamina propria of control ileum and colon and in diseased tissues. The majority of intraepithelial lymphocytes did not express HLA-DR. Epithelial cells of control colon did not express HLA-DR while epithelial cells of control ileal tissues and of diseased colonic and ileal specimens expressed HLA-DR antigen. Only small numbers of lamina propria T cells expressed HLA-DR in both control and disease tissues. There was intense expression of HLA-DR by monocytes and modest expression of HLA-DR by capillary and lymphatic endothelial cells. The induction of HLA-DR expression by diseased colonic epithelium and the observation that lymphatic endothelium expresses HLA-DR are new observations, and we established that Leu 7+ cells are present in very small numbers in both normal and diseased intestine and colon.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01318690
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  • 9
    Electronic Resource
    Electronic Resource
    Intraepithelial leukocytes of the intestinal mucosa in normal man and in Whipple's disease (1982)
    Springer
    Digestive diseases and sciences 27 (1982), S. 311-320 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Intraepithelial lymphocytes (IEL) of the intestinal mucosa of normal man and of patients with Whipple's disease were studied by light microscopy of 1-μm-thick sections, and by electron microscopy of thin sections. IEL in normal human intestine tend to be elongated in outline, have few cytoplasmic organelles, have compact nuclei, and are unattached to epithelial cells. IEL in Whipple's disease are more likely to be activated in appearance, ie, to be larger and to contain more cytoplasmic organelles than IEL of normal intestine. The number of IEL/100 intestinal epithelial cells is similar in normal man and in patients with Whipple's disease. Other intraepithelial (IE) cells found in normal intestine include eosinophils and mast cells, and we note for the first time the presence of IE macrophages. There are no “globule leukocytes” in the intestine of normal man or of patients with Whipple's disease. Other IE cells found in the intestine in Whipple's disease include eosinophils, polymorphonuclear (PMN) leukocytes, and macrophages in untreated disease and intraepithelial macrophages in treated disease. These IE cells may be involved in the acute and chronic immune responses of the intestine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01296750
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