ISSN:
1615-5947
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
2 . Cells were identified as ASMC by immunohistochemical analysis. Cells from passages 3-5 were exposed to glucose concentrations of 0.1 and 0.2% with and without insulin concentrations of 100 ng/mL and 1000 ng/mL, in the presence or absence of 200 μM of thiamine. Standard hemocytometry and 3H-thymidine incorporation quantified cell proliferation after incubation for 6 days and 24 hr, respectively. The data suggest that thiamine inhibits human infragenicular ASMC proliferation induced by high glucose and insulin. Vitamin B1 intake may prove important in delaying the atherosclerotic complications of diabetes.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s100169910007
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