ISSN:
1573-8221
Keywords:
chemotherapy
;
platinum preparations
;
nephrotoxicity
;
urinary proteins and enzymes
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Chemotherapy is an important method of antitumor therapy. Nephrotoxicity characteristic of many cytostatics, including platinum compounds, is a serious complication limiting the drug dose [4,5,7-9]. Platinum derivatives, in particular, cisplatin, are drugs of choice in the treatment of the majority of solid tumors. However, cisplatin induces a dose-dependent toxic damage to the kidneys [5,7,8,10].
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1015326614893
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