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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 24 (1976), S. 617-620 
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background:  Toluene diisocyanate (TDI)-induced asthma is a common cause of occupational asthma and it affects 5–15% of the exposed population suggesting an underlying genetic susceptibility.Methods:  To investigate the role of genetic factors in the development of TDI-induced asthma, we analyzed the distribution of human leukocyte antigen (HLA) class I genes and of tumor necrosis factor (TNF)-α A-308G polymorphism in 142 patients with TDI-induced asthma and in 50 asymptomatic exposed subjects.Results:  Neither the distribution of HLA class I antigens nor the distribution of TNF-α A-308G polymorphism was different between patients with TDI-induced asthma and asymptomatic exposed subjects.Conclusions:  These results suggest that HLA class I antigens and TNF-α A-308G are not associated with susceptibility or resistance to the development of TDI-induced asthma.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Mast cell chymase has the potential to be an important mediator of inflammation and remodelling in the asthmatic lung. Previous studies have examined association between promoter polymorphism of the chymase gene (CMA1) and allergic phenotypes but the significance of this polymorphism is unclear. We have examined association of a CMA1 variant in relation to asthma in a large UK Caucasian family cohort.Methods A polymorphism of the CMA1 gene promoter (−1903G/A) was genotyped in 341 asthmatic families and in 184 non-asthmatic adults recruited from the UK PCR-RFLP based genotyping. Association with asthma diagnosis, atopy, specific and total IgE, and atopy and asthma severity was examined.Results Case–control studies did not reveal a significant difference in allele frequency between asthmatics and controls. A significant association was found between CMA1 genotypes and total IgE levels in subjects with self-reported eczema that remained significant after correction for multiple testing (median total serum IgE GG 297 kU/L, GA 144 kU/L, AA 48.4 kU/L, Pc=0.0032).Conclusion These data suggest that CMA1 promoter polymorphism does not contribute to asthma susceptibility or severity but may be involved in regulating IgE levels in patients with eczema.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 42 (1991), S. 35-43 
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A thermosetting resin consisting of a mixture of vinyl-terminated oligomeric ethers was prepared by a two-step synthesis. This required the reaction of 1,4-bis (chloromethyl) benzene with the potassium salt of bisphenol A, and subsequent vinylation of the chloromethyl end groups by means of a Wittig reaction. The linear vinyl prepolymers were thermally crosslinked through their reactive styryl end groups (without the addition of catalyst) to produce castings and woven glass laminates. A study of the crosslinking process was carried out by differential scanning calorimetry (DSC). The water absorption and the thermooxidative stability of the crosslinked polymer were investigated. A styrene solution of the oligomeric ethers was also crosslinked, using benzoyl peroxide as a catalyst. The moisture absorption characteristics of the crosslinked styrene copolymer were compared with those of the crosslinked homopolymer. Both substances showed hydrophobic character.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 19 (1979), S. 590-595 
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A number of techniques have been developed in the past for the prediction of the dependence of the creep rupture life of polyethylene pipe on applied stress and temperature. It is now proposed that, using a modified form of the activated rate procss equation in which the activation volume varies predictably with temperature, a generalized equation may be derived which describes the “brittle” creep rupture curve over a range of temperatures, and also allows the use of a Larson-Miller type equation. Since the known “ductile” creep rupture curve at 20°C can be extrapolated from measurements carried out over a short period at room temperature in the laboratory, the intersection point between the extrapolated “ductile” curve and the calculated “brittle” curve can easily be calculated. If the proposed method is applied to creep rupture data obtained from Hoechst AG (GM5010, HDPE pipe) as an example, a transition at about 11 years is predicted.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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