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  • 1
    Electronic Resource
    Electronic Resource
    Ocular Toxoplasmosis: More Than Just What Meets the Eye (2002)
    Oxford, UK : Blackwell Science Ltd
    Scandinavian journal of immunology 55 (2002), S. 0 
    Details
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Toxoplasma gondii is an intracellular parasite whose life cycle may include the man as an intermediate host. Close to a billion people are infected with this parasite worldwide. Ocular lesions may occur in up to 25% of those individuals infected. The infection may occur intra-uterus, through the placenta when the mother is infected during pregnancy. The parasite may also infect adults after the ingestion of contaminated food products, most notably meats or water. We have shown that although congenital and post-natal (acquired) infection results in similar ocular lesions, the immunological mechanisms behind the development of disease are different. On the other hand, contrary to published data obtained in mice, we were unable to find evidence that the T. gondii express superantigen activity for human lymphocytes. Our findings are important because they suggest that superantigen activity is not important as a pathological mechanism in human disease. Our data also suggest that, whereas the ocular lesion caused by infection after birth is the result of an excessive or dysfunctional immune response, the lesions caused by congenital infection may be due to a lack of an appropriate response to the parasite.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3083.2002.01052.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Paracoccidioidomycosis with palpebral and conjunctival involvement (1975)
    Springer
    Mycopathologia 56 (1975), S. 21-24 
    Details
    ISSN: 1573-0832
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Resumo Um caso de paracoccidioidomicose pulmonar e linfática seguido de comprometimento conjuntivo-palpebral é estudado, em São Paulo. A literatura nacional é revista. As lesões oculares, mais frequentemente verificadas, na paracoccidioidomicose natural são descritas, minuciosamente. O pequeno número de casos humanos com comprometimento ocular é discutido. A severidade e a frequencia das lesões oculares em animais inoculados intracardiacamente, com cultivos de P. brasiliensis sugerem disseminação hematogênica ocular da paracoccidioidomicose humana.
    Notes: Abstract A case of paracoccidioidomycosis with ocular involvement is studied. Brazilian literature is reviewed. The scarcity of human ocular mycosis is commented on. The most frequent clinic aspects of ocular lesions in natural mycosis are described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00493578
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Choroidal granuloma caused by ‘Paracoccidioides brasiliensis’ (1982)
    Springer
    Mycopathologia 77 (1982), S. 37-41 
    Details
    ISSN: 1573-0832
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Resumo Paciente de 48 anos de idade com urn granuloma de coroide apresentou quadro sistêmico de paracoccidioidomicose provado por biópsia de lesão da rinofaringe. São discutidos os aspectos clínicos, diagnósticos diferenciais e prova terapêutica. Esta é a primeira vez que se descreve a angiografia fluoresceínica num caso destes.
    Notes: Abstract A 48 year-old-female with a choroidal granuloma presented a systemic picture of paracoccidioidomycosis proven by rhinopharyngeal biopsy. The clinical picture, the differential diagnosis and the therapeutic test are discussed. This is the first time that the fluorescein angiography is described in such cases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588655
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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