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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Scandinavian journal of immunology 43 (1996), S. 0 
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Amyloid susceptible C57BL/6 and partially amyloid resistant A/J mice, infected intraperitoneally with 250 alveolar hydatid cyst (AHC), the larval stage of a cestode parasite Echinococcus multilocularis, develop multiple organ amyloid deposits at approximately 1 and 4 weeks post infection (p.i.), respectively. Pooled spleens and livers from each mouse strain, at 8 and 10 weeks p.i., were used for the purification of protein AA utilizing a HiLoad Superdex 200 column equilibrated with 5 M guanidine-HCl. Protein AA from each mouse strain was separated on 16% Tris-tricine SDS-PAGE gels and immunoblotted with monospecific rabbit anti-mouse AA IgG; five and six immunoreactive AA subspecies were detected in the C57BL/6 and A/J materials, respectively. N-Terminal amino acid sequence analysis was performed on the bulk column-purified protein AA as well as on the electroblotted AA subspecies from each mouse strain. The results show a mixture of serum amyloid A1 (SAA1) and (SAA2)-derived AA protein from each mouse strain; SAA1-derived AA, although alluded to, has never been demonstrated as tissue deposits in mice. These findings suggest that the intense and persistent inflammatory processes in AHC-infected mice may have induced conversion of weakly amyloidogenic SAA1 to AA. This conversion could be detected by amino acid sequencing of electrophoretically separated AA subspecies.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Environmental geology 40 (2000), S. 121-134 
    ISSN: 1432-0495
    Keywords: Keywords Contamination ; Dereliction ; Desk studies ; Foundation remnants ; Rehabilitation ; Site investigation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  Contaminated and possibly hazardous ground represents a problem in all of the industrialized countries of the world. The investigation of a site that is suspected of being contaminated differs somewhat from a routine site investigation. Sampling of soils, groundwater and gas-producing material may be required. Various precautions may be necessary in doing this and operatives may have to wear protective clothing. Four case histories have been chosen to illustrate different aspects of the rehabilitation of abandoned contaminated land, namely, investigation, assessment, ground treatment and redevelopment. The first comes from Leeds in West Yorkshire, England, and outlines how a site investigation was undertaken and the nature of the contamination present, together with a note on the suggested redevelopment. The remaining three case histories are taken from the heavily industrialized district of the Ruhr in Germany, where extensive mining of coal and associated industries were developed from the mid-19th century onwards. The first considers the site of the former Graf Moltke mine near Essen. In this instance, the somewhat novel methods of data assessment and ground treatment are dealt with. The Mont Cenis site at Herne-Sodingen is one of the more notable old mining/industrial sites undergoing redevelopment in the state of North Rhine Westphalia. Hence, the case history concentrates of this aspect of rehabilitation. This involves not only the construction of new and interesting structures but an attempt to reduce energy consumption in an attempt to effect the concept of sustainable development of an urban area. The last example deals with the abandoned site of the Minister Achenbach mine at Lünen, where the ground conditions were further complicated by the presence of old bomb craters that had been filled with a variety of materials. In addition, because of the suspected presence of former foundation structures in the ground an electromagnetic survey was carried out across part of the site, the areas of high conductivity suggesting their presence.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2013
    Keywords: Metabolic Cold Response ; Shivering ; Leg Blood Flow ; Leg Oxygen Uptake
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. Total oxygen consumption (totalVO2), leg blood flow (legQ V) and leg oxygen uptake (legVO2) were measured in young steers each exposed to thermoneutral and moderately cold environments on the same day. 2. Cold sufficient to double resting totalVO2 caused a 3 to 6-fold increase in legQ Va 11/2 to 4-fold increase in leg arteriovenous oxygen saturation difference (SO2 A-EIV) and a small but significant elevation in haemoglobin concentration, resulting in a 5 to 24-fold increase in legVO2. This represented a 3 to 12-fold increase in the contribution of the hind leg to totalVO2. 3. These results were unaffected by whether thermoneutrality preceded cold orvice versa. 4. TotalVO2 was significantly correlated with legQ V, legVO2 and SO2 A-EIV in both environments. Regression analysis showed that during cold exposure legVO2 varied with legQ V, rather than SO2 A-EIV. 5. The metabolic response to cold of the hind leg is attributed to shivering skeletal muscle, and is shown to contribute substantially (15% per leg) to the response of the whole animal.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Educational studies in mathematics 10 (1979), S. 361-387 
    ISSN: 1573-0816
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Educational studies in mathematics 16 (1985), S. 103-110 
    ISSN: 1573-0816
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Educational studies in mathematics 7 (1976), S. 23-40 
    ISSN: 1573-0816
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Journal of Morphology 48 (1929), S. 611-625 
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: By the use of a new technique it was possible to demonstrate the Golgi granules about the idiosome of spermatids and in the so-called Golgi bead of the mature spermatozoon. Other osmiophile granules in the cytoplasm, assumed to be Golgi granules, aggregate during metamorphosis into groups which formed neutral fat spheres, giving stains with both sudan III and scharlach R. Evidence is adduced supporting the view that the Golgi apparatus is a lipin and probably a phospholipin. The fat spheres produced are probably a result of fatty degeneration in the residual body of the spermatid. They may also serve as the source of lipin in Popa's ‘Lipo-gel’ phenomenon.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 133 (1972), S. 143-163 
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Light and electron microscopy were used to study the morphology of adipose cells in newborn Merino lambs (Ovis aries). Postnatal changes in morphology were also examined in naturally fed Merino lambs held at 26°C or at 3°C for up to 32 days from the time of birth, and in lambs fasted for up to three days at 26°C or at 3°C since birth.All adipose cells examined in the newborn lambs showed the morphological characteristics of brown adipose cells; no white adipose cells could be found. The brown adipose tissue in normally fed lambs was replaced progressively by white adipose tissue during the first two or three weeks of life, and this replacement was retarded in the lambs held at 3°C. During replacement a continuous spectrum of cells with morphological characteristics between those of brown and white adipose cells were seen. No degenerating brown adipose cells were observed; and, apart from brown adipose cells, no cells were identified that could have been precursors of white adipose cells. This evidence suggests that in various body regions of lambs white adipose cells are derived from brown adipose cells.Lambs fasted at 3°C or under conditions that approached thermoneutrality (26°C) showed rapid depletion of lipid from brown adipose cells; hence brown adipose tissue of the lamb differs from that in the newborn rabbit in which this tissue is not readily depleted of fat during starvation under thermoneutral conditions.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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