ISSN:
1573-9171
Keywords:
asymmetrical synthesis
;
pentafluorobenzaldehyde
;
Schiffbase
;
fluorine-substituted β-phenylserines
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract Reaction of pentafluorobenzaldehyde with a Ni(II) complex of a Schiff base formed from glycine and (S)-2-[N-(benzylprolyl)amino]benzophenone yields, depending on the reaction conditions, the hitherto unknown, diastereo-and enantiomerically pure amino acids 2R,3S-β-(4-methoxytetrafluorophenyl)serine, 2S,3R-β-(4-methoxytetrafluorophenyl)serine, 2S,3S-β-(pentafluorophenyl)serine, and 2S,3R-β-(pentafluorophenyl)serine.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00863081
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