ISSN:
1573-8353
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The reaction of a polysubstituted 3,5-dimethylene-4-piperidone with aliphatic diamines leads to macrocyclic products, namely, 3,3′,5,5′-di(methylaminoalkyl-aminomethyl)-bridged bis(piperidones). The latter compounds are formed as mixtures of cis, trans-isomers, and isolated in the form of cis,cis-isomers. 13C-NMR spectral analysis has shown that these compounds also exhibit characteristic syn-anti isomerism associated with the relative orientation of the 3,5-substituents on opposite piperidone rings.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00478137
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