ISSN:
1573-8221
Keywords:
emotional stress
;
brain catecholamines
;
arterial blood pressure
;
locus coeruleus
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract To study central neurochemical mechanisms leading to a disturbance of self-regulation of the arterial blood pressure (BP) under conditions of emotional stress the dynamics of BP and the catecholamine level in different parts of the brain were studied in August and Wistar rats after immobilization for 2 h. The BP level was virtually indistinguishable from normal throughout the experiment. The catecholamine concentration in the hypothalamus, mesencephalon, the region of the isthmus cerebri, and the medulla was significantly changed. it is suggested that the mechanism of the changes in catecholamine concentration during stress in rats of both strains is similar in the region of the hypothalamus and medulla. Activity of the noradrenalinsynthesizing neurons of the isthmus cerbri and of the dopamine-synthesizing neurons of the mesencephalon in the rats of these two strains, however, is specific, and that is evidently one of the factors responsible for differences in the resistance of cardiovascular functions in the later stages of immobilization.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00799257
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