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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of organic chemistry 41 (1976), S. 2506-2507 
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1459
    Keywords: Alzheimer's disease ; Dementia ; Magnetic resonance imaging ; High signal lesions ; Leukoaraiosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The pathophysiology and clinical significance of high signal lesions, visualized on magnetic resonance imaging (MRI) in patients with Alzheimer's disease (AD), remain controversial. Since they are known to correlate with vascular disease and vascular risk factors, we reviewed the clinical correlates of periventricular high signal (PVH) and subcortical white matter lesions (WML) in a sample of 106 patients with probable AD, excluding persons with treated vascular risk factors or symptomatic cerebrovascular and cardiovascular disease. Grade 2 PVH were seen in 26 (25%) and scattered WML were identified in 29 (18%). PHV were associated with advancing age and gait disturbance. WML were associated with gait disturbance and incontinence. Neither radiologic finding was related to dementia severity. The findings suggest that these lesions are common in patients with AD even when those with evidence of cerebrovascular disease are excluded; their presence, therefore, should not preclude a diagnosis of AD. Additionally, the data suggest that HSL on MRI may be one of many risk factors associated with functional disability in persons with probable AD.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-2932
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract A national scale assessment of the effects of acid deposition on aquatic resources is currently unavailable for the United States. A more limited assessment has been performed in three potentially sensitive geographical regions the Adirondack Mountains of New York, the Southern Blue Ridge Province of North Carolina, Tennessee and Georgia, and the Upper Midwest of Minnesota, Wisconsin and Michigan. A series of questions organized the assessment, and historical and current data from each region were employed to address the questions. Where possible, independent data sets were used singly and in combination within a given case study area, to respond to the questions and to provide an estimate of confidence. Conclusions among regions were also compared. In general, the impact of acid deposition on aquatic resources is difficult to detect, but positive correlations between atmospheric deposition and effects do exist. Thus, there is evidence to suggest that acid deposition is at least partially responsible for the acidification of aquatic resources. The extent of acidification, however, varies from region to region. The Adirondacks appear to represent the region of greatest impact, but independent studies indicate that the area of acidified lakes is a small percentage of the total resource. Despite the observation of minimal damage, application of damage estimates from the Adirondacks to other regions would be inappropriate. Future Assessments will seek to predict the rate of acidification of watersheds with other regional characteristics under alternative loading scenarios.
    Type of Medium: Electronic Resource
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