Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    A NEW PURIFICATION PROCEDURE AND BIOLOGICAL PROPERTIES OF SUBSTANCE P (1963)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 104 (1963), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1963.tb17682.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Catecholamine transport through a lipid barrier (1974)
    [s.l.] : Nature Publishing Group
    Nature 248 (1974), S. 604-606 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Permeation studies were carried out at 37 C with commercially available equipment (resorption model of Stricker, SM 16750, Sartorius-Membranfilter GmbH, Gottingen), consisting of a diffusion cell with two compartments, A and B, of equal size (100 ml) separated by an artificial lipid barrier, and a ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/248604a0
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Physico-chemical properties of 5-hydroxytryptamine organelles of blood platelets (1969)
    Springer
    Inflammation research 1 (1969), S. 35-38 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract 5-Hydroxytryptamine (5-HT) together with adenosinetriphosphate (ATP) in aqueous solutions forms micelles of substantially higher apparent molecular weights than tryptamine or histamine in equiconcentrated solutions, aggregation being further enhanced by calcium and magnesium. The aggregation between 5-HT and ATP increases with decreasing temperature. Ultraviolet spectroscopy confirms that the solute in 5-HT organelles consists mainly of 5-HT and ATP. Appreciable amounts of calcium and magnesium are present as well. Isolated intact 5-HT organelles take up more 5-HT than tryptamine or histamine. It is concluded that biogenic amines are stored in the 5-HT organelles together with ATP in the form of micelles. These also bind calcium and magnesium. The rather specific uptake of 5-HT by the organelles may be connected with micelle formation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01990018
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Metal-dependent Aggregation of Biogenic Amines: A Hypothesis for their Storage and Release (1969)
    [s.l.] : Nature Publishing Group
    Nature 224 (1969), S. 281-283 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] 17 per cent w/w aqueous solutions of biogenic amines and ATP in a molar ratio of about 3 : 1 were chosen as a model. Similar3 and higher4 ratios have been determined in vivo. Hydrochlorides of mono and bivalent cations in various concentrations were added to the aqueous solutions, which had a pH of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/224281a0
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Interaction of proteins with aggregates of catecholamines and nucleotides: possible biological implications (1971)
    Springer
    Inflammation research 2 (1971), S. 65-68 
    Details
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Aggregates of noradrenaline and adenosine-5′-triphosphate (ATP) sediment jointly with gelatine on analytical ultracentrifugation. The sediumentation rate of this misture is higher than that of gelatine or of the aggregates alone. Furthermore, gelatine causes an increase in volume of the bottom phase which separates in aqueous solutions of ATP, noradrenaline and calcium. These effects are not obtained with the globular protein albumin. It is concluded that gelatine reversibly binds noradrenaline-ATP aggregates. Since the chromogranins have similar physicochemical properties to gelatine, an interaction of these proteins with aggregates of ATP and noradrenaline may be anticipated to occur in the adrenal chromaffin granules.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01965384
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    A possible mechanism for uptake of biogenic amines by storage organelles: Incorporation into nucleotide-metal aggregates (1971)
    Springer
    Cellular and molecular life sciences 27 (1971), S. 917-918 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Analytische Ultrazentrifugation ergibt, dass Adenosin-5′-triphosphat und Guanosin-5′-triphosphat in Gegenwart von Ca und Mg hochmolekulare Aggregate bilden. Die scheinbaren mittleren Molekulargewichte dieser Aggregate nehmen nach Zusatz von 5-Hydroxytryptamin oder Noradrenalin stark zu. Es wird daraus geschlossen, dass Nucleotidaggregate biogene Amine inkorporieren, wobei Nucleotid-Aminaggregate entstehen. Dies erklärt möglicherweise die Aufnahme und Speicherung von biogenen Aminen in nucleotidhaltigen subzellulären Organellen, z.B. von Blutplättchen, Nebennierenmark und noradrenergen Nerven.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02135742
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    New aspects on the storage of 5-hydroxytryptamine in blood platelets (1971)
    Springer
    Cellular and molecular life sciences 27 (1971), S. 993-1002 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Blutplättchen verschiedener Spezies speichern 5-Hydroxytryptamin zusammen mit Nukleotiden (hauptsächlich Adenosin- und Guanosin-5′-Triphosphat) und bivalenten Kationen (Ca und Mg) in spezifischen, subzellulären Organellen, welche elektronenoptisch eine starke Osmiophilie aufweisen. Speicherstellen für 5HT scheinen bereits in den Megakaryozyten vorhanden zu sein, da in diesen Zellen nach Zufuhr von exogenem 5HT osmiophile Organellen erscheinen, die denjenigen der Plättchen entsprechen. Die Aufnahme von biogenen Monoaminen durch isolierte Speicherorganellen hängt von der chemischen Struktur der Amine und der Temperarur ab; es bestehen keine Anhaltspunkte für einen aktiven 5HT-Transport. Analystische Ultrazentrifugation des Inhalts von isolierten Speicherorganellen von Kaninchen-Blutplättchen sowie von artifiziellen Lösungen ergibt, dass 5HT wahrscheinlich in Form hochmolekularer, gemischter Aggregate mit Nukleotiden und bivalenten Kationen akkumuliert. Die Bildung solcher Aggregate erklärt die osmotische Stabilität sowie möglicherweise andere biologische Eigenschaften der Speicherorganellen vor allem bezüglich Aufnahme von 5HT und dessen Freisetzung durch gewisse Substanzen, z. B. Tyramin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02138839
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Interaction of aggregated catecholamines and nucleotides with intragranular proteins (1973)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 277 (1973), S. 291-296 
    Details
    ISSN: 1432-1912
    Keywords: Catecholamine Storage ; Catecholamine-Nucleotide Aggregation ; Interaction with Intragranular Proteins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Analytical ultracentrifugation at different sets of conditions in the temperature range between 10 and 34° C shows that mixtures of l-noradrenaline and adenosine-5′-triphosphate in the presence of Ca2+ always sediment jointly, i.e. with only one single schlieren peak together with intragranular expanded proteins obtained from bovine adrenal medulla. In contrast, two schlieren peaks are obtained on addition of a globular protein, such as serum albumin, to l-noradrenaline-Ca2-adenosine-5′-triphosphate mixtures. It is concluded that aggregates of l-noradrenaline and adenosine-5′-triphosphate interact with the expanded proteins present in the catecholamine storage organelles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00505667
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...