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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Medical microbiology and immunology 151 (1965), S. 291-310 
    ISSN: 1432-1831
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Certain antisera contain two antibodies directed against two different antigenic determinants of the human haptoglobin molecule. They can be separated by absorption methods. One of these antibodies can precipitate haptoglobin only if it is free of, or only partially saturated with hemoglobin. The other antibody precipitates haptoglobin independent of the degree of saturation with hemoglobin. In contrast to these findings the inherited haptoglobin variant Hp Marburg is precipitated by both of these antibodies even after complete saturation with hemoglobin.
    Notes: Zusammenfassung Bestimmte Antiseren enthalten zwei durch. Absorptionsversuche trennbare Antikörper gegen zwei verschiedene Antigendeterminanten des Haptoglobinmoleküls. Einer dieser Antikörper präcipitiert das Hp der drei genetischen Gruppen nur, wenn dieses in freier oder nur partiell mit Hb gesättigter Form vorliegt. Der andere Antikörper präcipitiert Hp unabhängig vom Hb-Sättigungsgrad. Im Gegensatz zu normalem Hp wird eine als Hp-Marburg bezeichnete, erbliche Hp-Variante vonbeiden Antikörpern auch in Hb-gesättigtem Zustand präcipitiert.
    Type of Medium: Electronic Resource
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