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Identification of harman in the rat arcuate nucleus (1980)

Shoemaker, D. W. ; Cummins, J. T. ; Bidder, T. G. ; [et al.]

Springer

Naunyn-Schmiedeberg's archives of pharmacology 310 (1980), S. 227-230

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ISSN: 1432-1912

Keywords: β-Carboline ; Harman ; Arcuate nucleus ; Neuroendocrinology

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary This communication describes the presence of 1-methyl-β-carboline (harman) in the hypophysiotropic area of the hypothalamus which incorporates the arcuate nucleus. Diethyl ether extracts of boratebuffered arcuate homogenates were subjected to silica column chromatography and thin-layer chromatography (TLC). Identification of the β-carboline was accomplished by use of fluorescent spectrometry, gas chromatography (GC), mass spectrometry (MS) and combined gas chromatography-mass spectrometry (GC-MS).

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00499914

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