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  • 1
    Electronic Resource
    Electronic Resource
    Permeability of the bladder mucosa to thiotepa, adriamycin, and daunomycin in men and rabbits (1976)
    Springer
    Urological research 4 (1976), S. 9-13 
    Details
    ISSN: 1434-0879
    Keywords: Cancer chemotherapy ; Vesical absorption ; Adriamycin ; Thiotepa ; Daunomycin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The permeability of the bladder mucosa to thiotepa and to the anthraquinonic antibiotics, adriamycin and daunomycin, was investigated both in humans and in experimental animals. Instillations in rabbits were performed either in intact males or in animals with ligated ureters. Absorption of thiotepa was significantly higher than that of the antibiotics both in men and in rabbits. Furthermore a qualitative difference was observed in rabbits in relation to time and with regard to fixation to vesical tissues. In man, absorption was highest after transurethral surgery. It was also increased in cases with extensive anaplastic tumours or in the presence of acute inflammatory reactions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00256129
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Experimental techniques for testing the sensitivity of bladder tumours to antineoplastic drugs (1973)
    Springer
    Urological research 1 (1973), S. 60-66 
    Details
    ISSN: 1434-0879
    Keywords: Bladder papilloma ; bladder carcinoma ; tomour chemotherapy ; screening of anticancer compounds
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A number of laboratory tests can be employed to examine the sensitivity of human bladder tumour cells to various chemotherapeutic agents.-Their principles and methods, and some preliminary results, are described with special reference to certain in vitro and in vivo cytotoxicity tests and to heterotransplantation in the hamster. Satisfactory agreement has sometimes been observed between experimental results and clinical responses, but our experience is still very limited.-The employment of several such tests would probably lead to a greater degree of reliability in the laboratory assessment of the sensitivity of bladder tumours to cytotoxic drugs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00256120
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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