ISSN:
1432-2307
Keywords:
Key words Adenovirus
;
Liver pathology
;
Electron microscopy
;
AIDS
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Adenovirus-induced liver necrosis is rare. Before the era of AIDS (acquired immunodeficiency syndrome) this entity was seen predominantly in infants suffering from inborn immunodeficiency syndromes or from iatrogenic immunosuppression because of bone marrow or liver transplantation. Here, we report a case of a 30-year-old woman with AIDS who developed fever and rapidly progressing liver failure. A frozen section from a needle biopsy of the liver allowed a quick diagnosis of viral liver necrosis. The light-microscopic and electron microscopic aspects were typical of adenovirus infection and should be known to the surgical pathologist. The diagnosis was confirmed by immunohistochemistry and DNA hybridization analysis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004280050125
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