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  • 1
    Electronic Resource
    Electronic Resource
    Family History and Hormones in Stepwise Mammary Carcinogenesis (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 464 (1986), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1986.tb16016.x
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  • 2
    Electronic Resource
    Electronic Resource
    Homology between human breast tumour RNA and mouse mammary tumour virus genome (1974)
    [s.l.] : Nature Publishing Group
    Nature 249 (1974), S. 565-567 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We have used single-strand specific nuclease (Si) from Aspergillus oryzae6 for the detection of hybrid formation. This enzyme specifically degrades single-stranded nucleic acids but not double stranded nucleic acids or DNA-RNA hybrids. Highly radioactive, complementary and predominantly ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/249565a0
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  • 3
    Electronic Resource
    Electronic Resource
    Possible immunological implications of an association between the stages of first and second independent breast cancers (1984)
    Springer
    Breast cancer research and treatment 4 (1984), S. 95-103 
    Details
    ISSN: 1573-7217
    Keywords: breast cancer ; immunology ; stage of disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Concepts regarding cell-mediated immunity and breast cancer are reviewed. Patients having in situ breast cancers have been found by in vivo and in vitro measurements to have cell-mediated immunity to autologous and homologous in situ breast cancer tissue which may last for some time after diagnosis. These observations suggest that antigenically similar cancers arising subsequently in the contralateral breast should be less likely to progress beyound the in situ stage and, if they do become invasive, should exhibit prognostically favorable signs of cell-mediated immunity, e.g. sinus histiocytosis in the lymph nodes and/or lymphoid infiltrate and perivenous lymphoid infiltrate associated with the primary tumor. Cell-mediated immunity has also been shown to be negatively associated with stage of disease at diagnosis for invasive cancers, i.e. the proportion of patients exhibiting cell-mediated immunity decreases as the stage at diagnosis increases. These observations suggest that the stages of independent breast cancers occurring in the same woman should be positively correlated. Data from the SEER Program of the National Cancer Institute were examined in this regard and a strong positive association between the stage of first and second independent primary breast cancers was found with the effect on the stage of a second breast cancer following a first invasive breast cancer appearing to decrease with time subsequent to diagnosis. These observations are consistent with the immunogenicity of breast cancer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01806391
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    Paper (German National Licenses)
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