ISSN:
0003-276X
Keywords:
Life and Medical Sciences
;
Cell & Developmental Biology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
Notes:
Ova were removed from donors 63-68 hours after ovulation and placed in the uteri of pseudopregnant recipients of the same pregnancy age. In transfers of ova from young (2 1/2-6 month) to old (14-18 month) golden hamsters, only 8.3% developed into term fetuses. From old donors to young recipients, 4.5% of ova developed to term fetuses. In transfers of ova from young donors to young recipients, 49.2% of ova developed into term fetuses. There was no significant difference in percentage of fetal development between the two groups containing old females. The difference between these and the control (young to young) group was highly significant.There was a significantly lower number of ova recovered from old donors. At time of transfer, over one-sixth of the ova from old donors consisted of only one to four cells. At seven and one-half days, embryos developing from ova of old donors in uteri of young recipients were retarded and malformed.It is concluded that while the uterine environment in old hamsters appears inadequate to foster normal fetal development, there are also fewer ova ovulated in old females and these ova more frequently develop abnormally.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/ar.1091500409
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