ISSN:
0538-8066
Keywords:
Chemistry
;
Physical Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Permanganate ion rapidly oxidizes the thiol group in 2-thiouracils (2,3-dihydro-2-thioxo-4(1H)-pyrimidinones, 4-hydroxy-2-pyrimidinethiols) to the corresponding uracil-2-sulfonates in phosphate-buffered solutions. The oxidations, which are first order in oxidant and first order in reductants, are characterized by relatively small energies of activation (Ea ≅ 4.3-6.7kcal/mol) and relatively large negative entropies of activation (ΔS
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/kin.550100902
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