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  • 1
    ISSN: 1432-0460
    Keywords: Pharynx, neuropeptides ; Immunocytochemistry, pharynx
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The distribution of peptide-containing nerve fibers in the pharyngeal region of rabbits was studied by immunocytochemistry. Neuropeptide Y (NPY)-containing fibers were numerous around blood vessels and moderate in number among bundles of striated muscle fibers. A few NPY-containing fibers were seen around seromucous glands and beneath the epithelium. Nerve fibers containing vasoactive intestinal peptide (VIP) were numerous around seromucous glands and moderate in number around blood vessels, bundles of muscle, and in the subepithelial layer. A few nerve fibers containing substance P (SP) were seen around blood vessels, seromucous glands, among bundles of muscle, and in the subepithelial layer. Nerve fibers containing calcitonin gene-related peptide (CGRP) were numerous. They were distributed close to blood vessels, among bundles of muscle, in the subepithelial layer, and within the epithelium. A conspicuous finding was the occurrence of CGRP within motor end plates of striated muscle.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Dysphagia 3 (1988), S. 69-72 
    ISSN: 1432-0460
    Keywords: Pharynx physiology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To study the influence of bolus size on pharyngeal swallow, 20 dysphagic patients and 10 nondysphagic volunteers were examined cineradiographically while swallowing a bolus of 2.5, 5, 10, and 20 ml. Ten patients and 10 volunteers swallowed boluses in increasing volume while 10 patients swallowed boluses of decreasing volume. The movement of the hyoid bone occurred in a two-step fashion irrespective of the bolus size, and in all individuals. The speed of the apex of the bolus through the pharynx, measured by frame counting, increased with increasing size of the bolus. The speed of the peristaltic wave, as measured between vallecula and the PE segment, did not change with bolus size. Boluses of 10 or 20 ml caused penetration of barium into the larynx in 7 of the patients but in none of the volunteers. Our results suggest that pharyngeal constrictor activity, in terms of speed of peristalsis, is constant and not influenced by bolus volume.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Dysphagia 2 (1988), S. 140-144 
    ISSN: 1432-0460
    Keywords: Pharynx, radiography ; Pharynx, physiology ; Constrictor ; Swallowing ; Dysphagia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In order to define the influence of age on pharyngeal constrictor peristalsis, four groups of individuals were examined with cineradiography (50 frames/s) during barium swallow. The speed varied between 6.3 and 21.3 cm/s (mean, 10.5). There was no significant difference between young nondysphagic volunteers and the three groups of dysphagic patients ages under 40, between 50 and 60, and over 75 years of age). However, the intrapersonal variation of peristaltic speed during three different swallows was small in young nondysphagic volunteers and large in dysphagic patients. The variation increased with age. Variation in speed is easy to register during cineradiography and should be considered as a criterion for definition of pharyngeal motor performance in dysphagic patients.
    Type of Medium: Electronic Resource
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