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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International urology and nephrology 8 (1976), S. 79-85 
    ISSN: 1573-2584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Three cases of uraemic haemorrhagic pericarditis observed during haemodialysis treatment are described. The condition is explained with uraemic toxicosis, cyclic heparinaemia resulting from dialysis, deficient thrombocyte function, and decreased capillary resistance. The clinical appearance of haemorrhagic pericarditis was not typical in any of the cases. Two patients died, while in one patient partial pericardiectomy was performed with success.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International urology and nephrology 4 (1972), S. 303-316 
    ISSN: 1573-2584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Three cases of pulmonary haemorrhage associated with various forms of nephropathy have been studied, and 15 laboratory tests have been carried out to analyse the observed coagulation defects. Also three kinds of capillary tests have been performed. Goodpasture's syndrome. Laboratory tests pointed to hypercoagulability. Anomalies characteristic of consumption coagulopathy were observed in the terminal phase. Bleeding tendency appeared to be due to capillary damage. Lupus nephropathy. Haemorrhage of the lungs, brain, skin and eyeground was caused by thrombocytopenia. Malignant nephrosclerosis. The disease was marked by hyperfibrinogenaemia and diminished prothrombin consumption. Disturbance of thromboplastin production may have been a pathogenetic factor of the bleeding tendency. Although at least one capillary test was positive in all three cases, the coagulation studies made it probable that the pathomechanism of pulmonary haemorrhage is not the same in all nephropathies.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International urology and nephrology 11 (1979), S. 201-214 
    ISSN: 1573-2584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Nineteen patients with hereditary nephritis — members of six families — were studied for haemostasis on 11 occasions by the use of four capillary tests, 14 different blood coagulation tests and two different platelet function tests. Systemic capillaropathy was demonstrable in 8 out of 15 cases of the non-uraemic, and in all the 5 cases of the uraemic group. No completely normal blood coagulation was found in any of the cases and the coagulation disorders were never of exclusively haemorrhagic pattern. On the evidence of the complex studies, hypercoagulability as well as hyper-hypocoagulability were found in the uraemic and non-uraemic groups alike. Reduction in plasma fibrinolytic activity, elevation of the fibrinogen level and a shift of the thrombelastogram in the direction of thrombosis were demonstrable in the majority of the cases.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    International urology and nephrology 13 (1981), S. 375-385 
    ISSN: 1573-2584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A case is reported here, the clinical features of which raised the suspicion of Goodpasture's syndrome which was, however, at variance with the absence of antiglomerular basement membrane antibodies. Renal failure improved on immunosuppressive treatment and peritoneal dialysis, but the patient died of gastric haemorrhage from a peptic ulcer related to steroid treatment. Necropsy and microscopic study revealed abnormalities of liver and spleen, consistent with Wegener's granulomatosis. Immunohistologic studies of the kidney confirmed the presence of granular-type IgG deposits in the glomeruli. There were extensive fibrin deposits in the kidney. The ways and means for the differentiation of Wegener's granulomatosis from Goodpasture's syndrome, the potential pathogenetic role of immunocomplexes and fibrin deposits, and the therapeutic possibilities are discussed.
    Type of Medium: Electronic Resource
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