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  • 1
    Electronic Resource
    Electronic Resource
    Longevity : does family size matter? (1999)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 399 (1999), S. 522-522 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Sir Rudi Westendorp and Thomas Kirkwood conclude that women who live longer have fewer children. This can be ascribed almost entirely to an increase in the proportion of childless women in higher age groups. For those women that have children, the mean number of children ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/21059
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  • 2
    Electronic Resource
    Electronic Resource
    Changes in urinary taurine and hypotaurine excretion after two-thirds hepatectomy in the rat (1998)
    Springer
    Amino acids 15 (1998), S. 373-383 
    Details
    ISSN: 1438-2199
    Keywords: Amino acids ; Hepatectomy ; Hypotaurine ; Liver ; Taurine ; Urine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This study followed the time course of urinary taurine and hypotaurine excretion after two-thirds hepatectomy in rats. The excretion of both taurine and hypotaurine was elevated during 18th following the hepatectomy, with maximal excretion during the first 6h. Twelve and 24h after partial hepatectomy, the hepatic hypotaurine concentration was increased but liver taurine did not differ significantly from controls. No changes were observed in hypotaurine and taurine concentrations of heart, kidney, lung, muscle tissue and spleen. We postulate that partial hepatectomy induces a rapid increase of hepatic (hypo)taurine synthesis from precursor amino acids. The increased (hypo)taurine concentrations spill over into urine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01320901
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Discrepancies between gastric mucosal and urinary pepsinogen A patterns andin vitro synthesis and secretion of human pepsinogen (1988)
    Springer
    Digestive diseases and sciences 33 (1988), S. 135-143 
    Details
    ISSN: 1573-2568
    Keywords: pepsinogen ; phenotype ; gastric mucosa ; urine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The relationship between electrophoretic pepsinogen A (PGA) patterns from urine and gastric mucosa was studied in healthy volunteers and in patients with various gastric disorders. Discrepancies between urinary and gastric PGA patterns were found in 63.3% of the individuals. In 9% of the subjects with these discrepancies, the phenotype class in urine was different from that in gastric mucosa. The differences were found in all diagnostic groups. The highest frequency of differences was found in patients with gastric ulcer. The differences were not related to the serum PGA level. More than 80% of the differences were caused by a lower relative intensity of pepsinogen A fraction 5 (Pg5) in urine than in gastric mucosa. The possible origin of differences in PGA isozymogen patterns was studied by organ culture of gastric biopsies. In vitro synthesis and secretion of pepsinogens were studied by electrophoresis and autoradiography. The synthesis rate of PGA in biopsies of 1–2 mm diameter was 40–100 ng/hr. Posttranslational modification of PGA isozymogens was demonstrated. Pg2 and part of Pg4 probably are secondary products of Pg3 and Pg5, respectively. In some individuals the secretion rate ofPg3 was low compared to the other isozymogens. The conversion of Pg3 into Pg2 and the differential secretion of the isozymogens may explain some of the discrepancies between gastric and urinary PGA patterns.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01535723
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    Paper (German National Licenses)
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