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  • 1
    Electronic Resource
    Electronic Resource
    Effects of repetitive transcranial magnetic stimulation over dorsolateral prefrontal and posterior parietal cortex on memory-guided saccades (1998)
    Springer
    Experimental brain research 118 (1998), S. 197-204 
    Details
    ISSN: 1432-1106
    Keywords: Key words Transcranial magnetic stimulation ; Prefrontal cortex ; Parietal cortex ; Saccades ; Working memory
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  We investigated the role of the dorsolateral prefrontal cortex (DLPFC) and the posterior parietal cortex (PPC) in a visuospatial delayed-response task in humans. Repetitive transcranial magnetic stimulation (20 Hz, 0.5 s) was used to interfere temporarily with cortical activity in the DLPFC and PPC during the delay period. Omnidirectional memory-guided saccades with a 3-s delay were used as a quantifiable motor response to a visuospatial cue. The question addressed was whether repetitive transcranial magnetic stimulation (rTMS) over the DLPFC or PPC during the sensory of memory phase affects accuracy of memory-guided saccades. Stimulation over the primary motor cortex served as control. Stimulation over the DLPFC significantly impaired accuracy of memory-guided saccades in amplitude and direction. Stimulation over the PPC impaired accuracy of memory-guided saccades only when applied within the sensory phase (50 ms after cue offset), but not during the memory phase (500 ms after cue offset). These results provide further evidence for a parieto-frontal network controlling performance of visuospatial delayed-response tasks in humans. It can be concluded that within this network the DLPFC is mainly concerned with the mnemonic respresentation and the PPC with the sensory representation of spatially defined perceptual information.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002210050272
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  • 2
    Electronic Resource
    Electronic Resource
    Repetitive transkranielle Magnetstimulation (1997)
    Springer
    Der Nervenarzt 68 (1997), S. 778-784 
    Details
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Repetitive transkranielle Magnetstimulation ; Zerebraler Blutfluß ; Epilepsie ; fMRI ; Therapie ; Depression ; Key words Repetitive transcranial magnetic stimulation ; Cerebral blood flow ; Epilepsy ; fMRI ; Therapy ; Depression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Repetitive magnetic stimulation (rTMS) is a non-invasive, painless method to induce transient activation in circumscript regions of the human cortex. In contrast to TMS with single pulses rTMS allows a more effective stimulation of association cortex and temporary interference with the proper functioning of stimulated areas. Possible applications for examination of the functional anatomy of language lateralisation, memory functions and visual perception are discussed. Possible therapeutic for movement disorders and depression are discussed. On the basis of theoretical considerations and current experience rTMS induced epileptogenic effects are discussed and safety recommendations are given.
    Notes: Zusammenfassung Die repetitive transkranielle Magnetstimulation (rTMS) ist ein nichtinvasives, schmerzloses Verfahren, mit dem beim Menschen in umschriebene Kortexareale temporäre Reizeffekte ausgelöst werden können. Im Unterschied zur Stimulation mit Einzelreizen kann mit der rTMS effektiver mit Funktionen des Assoziationskortex interferiert werden. Neue Anwendungen für funktionell-anatomische Fragestellungen zu Sprachlateralisierung, Gedächtnisfunktionen und visueller Wahrnehmung werden dargestellt. Mögliche therapeutische Effekte für die Behandlung von Bewegungsstörungen und Depression werden beschrieben. Aufgrund theoretischer Überlegungen und bisheriger Erfahrungen wird das Risiko rTMS-induzierter epileptogener Effekte diskutiert und Empfehlungen zur Anwendungssicherheit gegeben.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001150050194
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  • 3
    Electronic Resource
    Electronic Resource
    An inviscid/viscous coupling approach for vortex flow field calculations (1992)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 14 (1992), S. 1437-1452 
    Details
    ISSN: 0271-2091
    Keywords: Vortex flow aerodynamics ; High angle of attack ; Delta wing ; Viscous vortex models ; Vortex separation and bursting ; Computational fluid dynamics ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A new computational approach is developed for the analysis of vortex-dominated flow fields around highly swept wings at high angles of attack. In this approach an inviscid Euler technology is coupled with viscous models, similar to inviscid/boundary layer coupling. The viscous nature of the vortex core is represented by an algebraic model derived from the Navier-Stokes equations. The approach also accounts for the effects of the viscous shear layer near a wing surface through a modified surface boundary condition. The inviscid/viscous coupling consistently provides improved predictions of leading edge separation, vortex bursting and secondary vortex formation at relatively low computational cost. Results for several cases are compared with wind tunnel tests and other Euler and Navier-Stokes solutions.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650141206
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    Paper (German National Licenses)
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