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  • 1
    Electronic Resource
    Electronic Resource
    Further studies of an epizootic of perch Perca fluviatilis L., of uncertain aetiology (1979)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 2 (1979), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Abstract. The geographical distribution of an epizootic of perch Perca fluviatilis L., characterized by severe epidermal lesions and marked fish kills, is described. A wide variety of fungal and bacterial infections were found in diseased fish but the evidence suggests that they were not the primary cause of this condition. The primary pathogenic agent (assuming that it exists) or predisposing environmental factor has yet to be discovered. The severity of this disease is illustrated by monitoring the course of the epizootic in the perch population in Windermere. All age groups of fish were affected during the course of one year although the fish at spawning time appeared to be particularly vulnerable. There was a dramatic increase in the perch mortality in Windermere in 1976 and it is estimated that over 98% of the adult population (over 1 million fish) died in that year.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1979.tb00172.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Isolation of infectious pancreatic necrosis virus from eels, Anguilla anguilla L., in the United Kingdom (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 4 (1981), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1981.tb01153.x
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  • 3
    Electronic Resource
    Electronic Resource
    Histopathological changes in the livers of dab, Limanda limanda (L.) (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 16 (1993), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Abstract. The dab, Limanda limanda (L.), is a common species of flatfish found in the shallow waters of the North Sea, particularly in inshore regions. Because of its distribution and habits, it is a useful species for investigations into the biological effects of marine pollution; it is also susceptible to certain, easily-detectable, gross diseases, including a variety of hepatic lesions, some of which are putative neoplasias. Investigations over the past 10 years on the histopathology of dab livers, have revealed that many lesions are associated with parasitic infections or trauma, and others include the presence of basophilic foci and putative adenoma as well as cell storage changes. The significance of these lesions is discussed in relation to other biological and physical data, and the necessity for histological evaluation is emphasized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1993.tb00863.x
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  • 4
    Electronic Resource
    Electronic Resource
    A study of the sequential clinical and pathological changes during proliferative kidney disease in rainbow trout, Salmo gairdneri Richardson (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 10 (1987), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Abstract. A histological study of 0+ rainbow trout, exposed to proliferative kidney disease (PKD) on an infected farm, showed evidence of infection from the beginning of June, gross pathological changes from the beginning of July, and clinical signs from mid-July. Evidence of healing was present in some samples from the second week of August. Kidney samples were divided into five grades (0–4) representing increasing severity of pathology. A sixth grade (H) was applied to kidneys showing signs of healing. The most frequent clinical signs were abdominal distension and exophthalmos. Melanosis, corneal cloudiness and ecchymoses were observed occasionally. Apart from renal enlargement, other internal gross pathological changes included ascites, gill and liver pallor, oedema, petechiation, and splenic enlargement. The majority of clinical signs and internal changes were only seen in fish with advanced renal swelling (grades 3 and 4). Histopathology was most marked in the kidney and was of three types: haemopoietic hyperplasia, vascular pathology and diffuse inflammatory change. Vascular changes, including occlusion of blood vessels in several organs and apparent haemoglobin crystallization, and destruction of renal excretory structures within areas of chronic diffuse inflammation were marked features of the histopathology in fish with clinical signs. The pathogenesis of PKD is discussed with reference to the histopathological changes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1987.tb01081.x
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  • 5
    Electronic Resource
    Electronic Resource
    The occurrence of proliferative kidney disease (PKD) in cultured and wild fish: further investigations (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 14 (1991), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Abstract. In an investigation of the occurrence of proliferative kidney disease (PKD) in freshwater fish other than rainbow trout, 18 species of wild fish and seven species of fish raised in cultivation wore sampled from waters where the disease occurred annually in rainbow trout, Oncorhynchus mykiss (Richardson). Results revealed that certain wild stocks of brown trout. Salmo trutta L., grayling, Thymallus thymallus L., and pike, Esox lucius L., were infected with PKD, as were cultivated Atlantic salmon, Salmo salar L., parr, brown trout and char, Salvelinus alpinus (L.). Microscopical examination revealed the presence of the PKX cell in these species and also intraluminal protozoa possibly related to the PKX cell, which were not found in the rainbow trout. Other species of freshwater fish had myxosporidan infections but, unlike PKD infection, there was little host/parasite tissue response. The PKX cell as a myxosporidan stage is discussed and the presence of the disease in wild fish is reported.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1991.tb00614.x
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  • 6
    Electronic Resource
    Electronic Resource
    Further consideration of the haematology of proliferative kidney disease (PKD) in rainbow trout, Salmo gairdneri Richardson (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 10 (1987), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Abstract. A study of selected haematological parameters in rainbow trout, Salmo gairdneri Richardson, exposed to proliferative kidney disease (PKD) under field conditions is described. Changes in the blood picture are related to kidney pathology at different stages of the disease. As extensive renal vascular pathology, haemoglobin crystallization and inflammatory lesions developed, there were progressive decreases in haemoglobin and packed cell volume values, erythrocyte numbers declined to less than 50% of those in control fish, and numbers of misshapen erythrocytes increased. Leucopenia, neutrophilia and thrombocytopenia developed, especially in oedematous fish. With recovery, most values were similar to those of control fish. In recovered, re-challenged fish, erythrocyte counts, packed cell volume and haemoglobin values decreased in infected fish compared with uninfected fish. The results of the study are compared with those of other authors and the type of anaemia in PKD is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1987.tb01094.x
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  • 7
    Electronic Resource
    Electronic Resource
    A survey of the prevalence and distribution of proliferative kidney disease (PKD) in England and Wales (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 4 (1981), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1981.tb01155.x
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Proliferative kidney disease of salmonid fish: a review (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 7 (1984), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Abstract A detailed review of proliferative kidney disease (PKD) in salmonids is presented. The introduction places the disease in a historical context. The various aspects of the disease are described from the existing literature, together with latest findings from current research. Particular emphasis is given to epidemiology, aetiology and pathology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1984.tb01201.x
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  • 9
    Electronic Resource
    Electronic Resource
    Histological variations of hepato-splenic organs from the North Sea dab, Limanda limanda (L.) (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 7 (1984), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Abstract. This study showed variations in the histological appearance of livers and spleens from the North Sea dab, Limanda limanda (L.), sampled during two cruises of the FFS Anton Dohrn (5–15 January 1981 and 12–23 October 1981). Samples were taken from the German Bight, Dogger Bank and Humber/Thames areas of the North Sea. The majority of livers and spleens were assumed to be normal; however, certain histopathological changes were noted which included the abundance and size of melanin–macrophage centres where Fe+++ was demonstrated, sites of focal necrosis, the presence of hepatic nodules, the occurrence of granulomas and hepatic hyperaemia. The areas containing Fe+++ in spleens were quantitatively assessed and found to be increased in size and frequency in dabs sampled from the Dogger Bank. It was also noted that the prevalence of hepatic nodules was higher in dabs from that same area. Although this study does not reveal reasons for the variations in prevalences of anomalies, the pathologies are discussed in relation to habitat and environmental conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1984.tb00931.x
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  • 10
    Electronic Resource
    Electronic Resource
    Ultrastructural aspects of PKX, the causative agent of proliferative kidney disease in rainbow trout, Salmo gairdneri Richardson (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 10 (1987), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1987.tb01078.x
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    Paper (German National Licenses)
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