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  • 1
    Electronic Resource
    Electronic Resource
    A severe coagulopathy following volume replacement with hydroxyethyl starch in a Jehovah's Witness (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 43 (1988), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Blood volume was maintained by an infusion of hydroxyethyl starch 2000 ml (Hespan: HES) during and for the first 28 hours after a major orthopaedic operation in a 13-year-old girl who was a Jehovah's Witness. This was responsible for a generalised clinical haemorrhagic state, an acquired coagulopathy associated with a shortened thrombin, prolonged prothrombin and activated partial thromboplastin times, and an acquired von Willebrand syndrome. The coagulation, after cessation of the infusion of HES, did not become normal until approximately 72 hours later.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1988.tb09021.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A reply (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 44 (1989), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1989.tb11116.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    A comparison of the laryngeal mask airway and Guedel airway, bag and facemask for manual ventilation following formal training (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 48 (1993), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Ten volunteers, with no previous experience of resuscitation, were formally trained in the use of the laryngeal mask airway and the oropharyngeal airway (Guedel), bag and facemask for manual ventilation of the lungs in 104 fit, anaesthetised adults. They then used both airways in turn. The order of insertion was randomly allocated, and the times taken for insertion were also recorded. Ventilation for each airway was deemed to be successful if an increase in end-tidal carbon dioxide partial pressure did not occur and arterial oxygen saturation remained greater than 90%. Success rates for the laryngeal mask airway and the Guedel airway, bag and facemask were 87% and 43% respectively (p 〈 0.001) and the average insertion times were 27.4 s (SEM 1.5) and 15.8 s (SEM 0.50) (no significant difference), respectively. The laryngeal mask airway proved to be easier to use for manual ventilation than the Guedel airway, bag and mask for inexperienced personnel who had received a period of formal training in both techniques.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1993.tb06909.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    The haemostatic effects of hydroxyethyl starch (HES) used as a volume expander (1985)
    Springer
    Intensive care medicine 11 (1985), S. 300-303 
    Details
    ISSN: 1432-1238
    Keywords: Hydroxyethyl starch (HES) ; Factor VIII complex ; Platelets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Hydroxyethyl starch (HES 450.000/0.7; Hespan 6.0 g/100 ml) was compared with standard crystalloid solutions in postoperative volume replacement in 20 patients undergoing routine orthopaedic surgery. The HES group showed no clinical evidence of haemorrhage and no laboratory evidence of significant haemostatic defects as assessed by standard coagulation tests, platelet aggregation and fibrinogen concentrations. There was a slight shortening in the thrombin time and a smaller increase in postoperative FVIII RAg and FVIII RCof levels in the HES group. HES is a safe and effective volume expander for postoperative use.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00273540
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Book reviews (1985)
    Springer
    Intensive care medicine 11 (1985), S. 166-166 
    Details
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00258548
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Fluid replacement in hypovolaemia (1985)
    Springer
    Intensive care medicine 11 (1985), S. 231-233 
    Details
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Conclusions The question of which fluid should be used to augment a falling blood volume has been investigated in several animal models and numerous clinical trials. The results do not indicate an ideal approach. Generally electrolyte solutions are not as good as the other products. Because of the demands on the transfusion service for plasma procurement whole blood is in limited supply. However, whole blood should be available for large acute haemorrhages in excess of 2 l. The synthetic macromolecular colloids are probably as good as albumen solutions and fall into two clinical categories. The first group increase the blood volume by an amount slightly greater than the volume infused but are rapidly eliminated so their clinical effects remain for only two to three hours. Of these solutions the modified gelatins are probably the colloid of choice. For a more prolonged volume expansion of up to 24–36 h the larger macromolecules are more ideal but with a less potent initial oncotic effect [7]. Hydroxyethyl starch seems the most suitable of these substances. Albumen solutions are considerably more expensive but, otherwise have properties of volume expansion intermediate to the two colloid groups and limiting side effects of similar overall frequency. The final choice depends on local availability, cost effectiveness and personal clinical experience.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00260349
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Book reviews (1983)
    Springer
    Intensive care medicine 9 (1983), S. 350-350 
    Details
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01692558
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    Paper (German National Licenses)
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