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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 68 (1997), S. 599-602 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We describe preliminary experiments designed to demonstrate the use of charge-coupled device (CCD) imagers as spectroscopic detectors of charged particles. A large-area front-illuminated imager made on p/p+ epitaxial material was irradiated with α particles with energies up to 5.5 MeV and protons up to 13 MeV. The charge per event agrees reasonably well with calculations that assume a collection zone comprising the p epilayer and the portion of the p+ substrate within a diffusion length of the p epilayer. The charge per event for these particles is relatively large, often exceeding the CCD well capacity in the case of α particles, and therefore some of the stressing requirements of other applications, such as low dark current and low read noise, are not essential in this case. The results indicate that CCD imagers are excellent candidates for applications such as charged-particle diagnostics of inertial confinement fusion implosions. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We describe the fabrication and performance of the first spatial light modulators (SLM's) which combine addressing in AlGaAs charge-coupled devices (CCD's) and electroabsorption effects in GaAs/AlGaAs multiple quantum wells (MQW's). One-dimensional, sixteen-stage, three-phase AlGaAs CCD's with semitransparent gates were fabricated on the surface of the SLM. The optical signal propagates normal to the surface and enters the SLM through the gates. The transmission of this signal through the MQW is then modulated according to the channel voltage of the CCD's. The maximum contrast ratio at 847 nm was measured to be 1.45:1 for these GaAs/AlGaAs -based SLM's.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Astronomy and Astrophysics 3 (1965), S. 275-296 
    ISSN: 0066-4146
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We have developed a low-noise, high-sensitivity charge-coupled-device (CCD) technology for imaging applications extending from the soft x-ray (1 A(ring)) to the near-infrared (10 000 A(ring)) regimes. We have also developed a fabrication technology for making back-illuminated versions of these devices with quantum efficiencies as high as 90% from 5000 to 7000 A(ring). Our efforts have focused on two devices, a 64×64 pixel back-illuminated imager with two output ports that operates at 2000 frames per second with 23 electrons read noise, and a larger device, with 420×420 pixel format, designed for lower frame rates with noise as low as 1.5 electrons and used at visible, UV, and x-ray wavelengths. Applications to plasma diagnostics include Thomson scattering and high-frame-rate imaging in the visible, as well as x-ray imaging and bolometry.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 69 (1958), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 120 (1989), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Plasma dehydroepiandrosterone sulphate, androstenedione, testosterone (T), dihydrotestosterone (DHT), and sex hormone binding globulin (SHBG) have been measured in 64 females and 26 males aged less than 25 years and with acne vulgaris. Oestradiol was measured in the males. Free T and free DHT were calculated. Acne was graded on three sites and the sebum excretion rate (SER) was measured in most patients. With the possible exception of free DHT, none of the plasma steroids or SHBG correlated with acne severity or with SER. Free DHT in the females showed a possible, but weak, correlation with total acne (r=0.25, P=0.07), but comparison with male data showed that this was not causative. The role of androgens in acne is permissive and plasma androgen measurements usually have no place in its management.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 117 (1987), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Azelaic acid is a natural product of Pityrosporum ovale; used topically it has been shown to be of benefit in acne by a marked antimicrobial effect against Propionibacterium acnes. No study to date, however, has included a placebo group. We have investigated 40 patients with clinical acne in a double-blind study; half received 20% azelaic acid cream and half the base cream. Assessments were made of total acne grade, lesions counts and side-effects.Azelaic acid was significantly better than placebo at 1, 2 and 3 months in improving overall acne grade (P 〈 0·01) and inflamed lesions (P 〈 0·001). Side-effects were minimal—the main drawback of the preparation was greasiness of its base.We also collaborated in a multicentre study involving 859 patients in which azelaic acid was compared with other treatments. It was found to be as effective as benzoyl peroxide, retinoic acid and oral tetracycline over an 8-month study. It gave a significantly lower incidence of dermatitis (P 〈 0·01) than either retinoic acid or benzoyl peroxide and, in contrast to the latter, it did not bleach clothes.We conclude that azelaic acid is a safe and beneficial topical treatment for acne vulgaris.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 114 (1986), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Four hundred and twenty patients with moderate to severe acne vulgaris were treated with oral erythromycin and topical benzoyl peroxide to determine the optimum dose regimes. Our results show that the response was significantly less in patients with a greater severity of acne, with truncal acne and in those with a higher sebum excretion rate. There was a significantly better clinical result in patients given ig erythromycin daily than in those given 0.5 g daily (plus topical therapy in both groups). The relapse rate on stopping antibiotics is also significantly less in patients given i g daily and this dosage did not produce any increase in side effects. We suggest that any patient requiring oral antibiotics should initially be given i g daily of erythromycin (or tetracycline) for up to six months, plus topical therapy.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 108 (1983), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In a double-blind clinical study in ninety-four subjects a 1.5% (w/v) erythromycin lotion was as effective as 5% (w/v) benzoyl peroxide gel in significantly reducing the number of small inflamed lesions and the overall acne severity. However, benzoyl peroxide also significantly reduced the number of non-inflamed lesions whereas erythromycin had no effect on these lesions. This study supports the view that, although topical erythromycin is of value in the treatment of mild or moderate acne vulgaris, long established, safe and effective remedies should not be replaced by topical antibiotics until more comparative studies and investigations on bacterial resistance have been completed.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 101 (1979), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Forty-eight patients participated in a 3-month double-blind study to compare the effect of orally administered zinc sulphate/citrate complex and tetracycline hydrochloride in acne vulgaris. Tetracycline significantly reduced the overall grade, and the number of non-inflamed lesions, papules and pustules by the third month. It also reduced significantly the non-inflamed lesions and papules at the end of the second month. In contrast, zinc therapy only had a significant effect on the pustules at the third month.The results indicate that tetracycline is far superior to the zinc complex in patients with moderately severe acne.
    Type of Medium: Electronic Resource
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