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  • 1
    Digitale Medien
    Digitale Medien
    METABOLIC EFFECTS OF TOPICAL SILVER NITRATE THERAPY IN BURNS COVERING MORE THAN FIFTEEN PERCENT OF THE BODY SURFACE (1968)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 150 (1968), S. 0 
    Details
    ISSN: 1749-6632
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Allgemeine Naturwissenschaft
    Notizen: Electrolyte and water balance studies have been carried out on 20 patients with total body surface burns ranging from 15 to 85%. All patients were treated with 0.5% aqueous AgNo3 applied directly and continuously to the burn wound. The balance studies showed that the loss of Na through the burn wound was directly related to the square area of burn surface and was constant from day to day. Based on this steady and predictable loss of Na in the uninfected burn, a formula has been derived predicting the daily Na replacement necessary to cover the obligatory loss via the burn wound plus the requirements of normal metabolism. This formula has provided an accurate prediction of daily Na requirements in the treatment of thermal burns of widely varying extent, in patients of widely different ages, as judged by water and electrolyte balance studies.The formula provides a useful guide to the level of Na replacement required. Exact tailoring must be carried out to fit the needs of each patient. The direct monitoring of the accuracy of Na replacement by way of the serum Na level has been found cumbersome but intermittently necessary. In the burn patient in metabolic balance and taking a reasonable diet, the level of urinary excretion of Na has been found to be an accurate prediction of serum Na level. A urinary excretion of 40 mEq of Na per liter or above has uniformly reflected a normal serum Na level. The urinary Na has been used as an indicator of accurate replacement therapy replacing the majority of serum Na determinations.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1749-6632.1968.tb14719.x
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  • 2
    Digitale Medien
    Digitale Medien
    Ventricular volume and ejection fraction in the diagnosis of the aetiology of low cardiac output in burned patients (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 41 (1986), S. 0 
    Details
    ISSN: 1365-2044
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Cardiovascular instability following burns may result from either cardiac or non-cardiac causes. We illustrate three cases in whom routine measurements of atrial filling pressures and cardiac output alone did not reject the adequacy of blood volume or the myocardial performance. In each instance, measurements of ventricular volume and ejection fraction by thermodilution technique or 99mTC ventriculography were useful to determine the actual causes of decreased cardiac output.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2044.1986.tb13276.x
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  • 3
    Digitale Medien
    Digitale Medien
    Artificial Skin (2000)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Medicine 51 (2000), S. 231-244 
    Details
    ISSN: 0066-4219
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Medizin
    Notizen: Abstract The skin is a complex organ that is difficult to replace when it is irreversibly damaged by burns, trauma, or disease. Although autologous skin transplantation remains the most common form of treatment in patients with significant skin loss, there are now a number of commercially available products that can be used to replace the skin temporarily or permanently. Here we describe several such products under the rubric "artificial skin," focusing on two types of technology that have been applied to the problem of permanent skin replacement.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1146/annurev.med.51.1.231
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  • 4
    Digitale Medien
    Digitale Medien
    Preventive Antibiotic Management in Surgery (1973)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Medicine 24 (1973), S. 289-294 
    Details
    ISSN: 0066-4219
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1146/annurev.me.24.020173.001445
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  • 5
    Digitale Medien
    Digitale Medien
    The Use of "Artificial Skin" for Burns (1987)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Medicine 38 (1987), S. 107-117 
    Details
    ISSN: 0066-4219
    Quelle: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Thema: Medizin
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1146/annurev.me.38.020187.000543
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  • 6
    Digitale Medien
    Digitale Medien
    White-light Three Dimensional Microscopy using Multiple-image Storing and Decoding (1971)
    [s.l.] : Nature Publishing Group
    Nature 231 (1971), S. 303-306 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] The problem of three dimensional microscopy has received considerable attention. Among the most recent methods, so called deep field microscopy1'2 consists of illuminating the specimen with a thin "sheet" of light, perpendicular to the optical axis of the microscope, and recording the topological ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/231303a0
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  • 7
    Digitale Medien
    Digitale Medien
    Sialic Acid-deficient α 1 -Acid Glycoprotein produced in Certain Pathological States (1964)
    [s.l.] : Nature Publishing Group
    Nature 204 (1964), S. 75-76 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] a!-Acid glycoprotein was isolated by a two-step procedure from certain blood specimens. First, the sera were fractionated according to a modification of the Cohn method 10 (ref. 6). Second, the resulting fractions VI2 were chromatographed on 'Amberlite I.R〈7-50'7 yielding o^-acid glycoprotein ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/204075a0
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  • 8
    Digitale Medien
    Digitale Medien
    Plant DNA patents in the hands of a few (1999)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 399 (1999), S. 405-406 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] SirConsolidation in the agrochemical and seed industry continues to shorten the list of owners of ‘enabling’ intellectual property for plant genetic modification and molecular biology. Six major groups of multinational companies are poised to develop and patent ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/20786
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  • 9
    Digitale Medien
    Digitale Medien
    Public-sector patents on human DNA (1997)
    [s.l.] : Macmillan Magazines Ltd.
    Nature 388 (1997), S. 709-709 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] Sir The increasing emphasis of genomics in therapeutic and diagnostic research and development (R&D) suggests a continuing dominant role for the pharmaceutical industry in patenting human DNA. Here we present new data that challenge this broadly accepted trend by ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/388709a0
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  • 10
    Digitale Medien
    Digitale Medien
    Crystallization and preliminary X-ray studies of recombinant horseradish peroxidase (1995)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 51 (1995), S. 121-123 
    Details
    ISSN: 1399-0047
    Quelle: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Thema: Chemie und Pharmazie , Geologie und Paläontologie , Physik
    Notizen: A non-glycosylated form of horseradish peroxidase c extracted from Escherichia coli inclusion bodies and refolded in the presence of haem and Ca2+ ions has been used to grow protein crystals suitable for X-ray diffraction analysis. The crystals are prisms in the trigonal space group P3112 or P3212 with a = b = 158.9 and c = 114.3 Å, and diffract to 1.9 Å. There are four molecules, each of 34 kDa, in the asymmetric unit. The molecules of the asymmetric unit are related by approximate translational symmetry, resulting in pseudo-centerings. Data to approximately 15 Å can thus be described by a lattice of a′ = b′ = 91.7 Å and c′ = 57.1 Å, α = β = 90° and γ = 120°, including four molecules.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1107/S0907444994008723
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