ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Synthesis and amoebicid properties of emetin analogs. Analysis of the new compounds by 13C-NMR. B/C-cis or trans-fused (±) 1-alkyl-3-desethyl-emetin.New 1-alkyl-3-desethyl-emetines were prepared for pharmacological purposes.The usual emetine synthesis sequence applied to cis-1-alkylbenzo [a]quinolizidin-2-ones afforded new cis-1-alkyl-3-desethyl-emetines.The trans-fused isomers were also prepared.The relative configuration are determined by 1H- and 13C-NMR. spectra.
Additional Material:
5 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19770600703
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