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  • 1
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Medicine 51 (2000), S. 393-406 
    ISSN: 0066-4219
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine
    Notes: Abstract Kidney transplant candidates increasingly are looking to their relatives, spouses, and even friends for a better chance at transplantation. The wait for a cadaver kidney might be 2-5 years. Although kidneys from well-matched family members have been transplanted with excellent results for many years, accepting living donors who are genetically unrelated to the patient has not been encouraged until recently. Results show that, among 1700 patients who received kidney transplants from living unrelated donors in the United States from 1995 through 1998, the one- and projected ten-year graft survival rates were 92% and 67%, respectively. These results are superior to the 87% and 50% rates for more than 26,000 cadaver kidney transplants during the same period. Risks to the donor are low (〈0.005% mortality and 〈0.3% serious complications) but not absent. Thus, motivated spouses, friends, and adopted or stepfamily members can play an important role in the rehabilitation of patients who need a kidney transplant.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 277 (1979), S. 663-665 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Table 1 Genetic mice constitution of recipient-donor-target strain combinations of used to prepare alloantisera and la polypeptides Strain Haplo type K A Regions of H-2 B J E C S D A.TH (Recipient) t2 s s s s s s s d A.TL BIO. HTT Donor Target tl t3 s s k s k k s s k k k k k k d d ...
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 281 (1979), S. 336-336 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR, - Rolf Zinkernagel is too modest (14 June, page 618). The revolution which he and David Katz started has changed our thinking about the 'MHC' (major histocompatibility complex) to an extent which makes nonsense of the conventional nomenclature used in the otherwise excellent book which he ...
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Partial N-terminal amino acid sequences of the Ia molecule encoded by theI-E orI-C (I-EC) subregion of theH- 2d haplotype are presented. Several homology relationships are apparent when these sequences are compared to the gene products of the mouseI- ECk andI-A subregions and to their human and guinea pig counterparts. Theβ polypeptide differs from the EC β k polypeptide in two of the seven positions at which they can be compared and shows moderate homology with its human p29 counterpart. Theα polypeptide is identical to the EC α k polypeptide in the eight positions which can be compared and is highly homologous to the human p34 polypeptide. The genetic implications of these observations are discussed.
    Type of Medium: Electronic Resource
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