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  • 1
    Electronic Resource
    Electronic Resource
    ACCELERATED RESTRUCTURING OF BEEF (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food quality 8 (1986), S. 0 
    Details
    ISSN: 1745-4557
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Restructured steaks manufactured by two comminution methods from prerigor electrically stimulated (PES) beef, nonstimulated counterparts (NES) and postrigor non-electrically stimulated (C) samples were compared. After frozen storage for 0,14, and 42 days, samples were subjectively evaluated for appearance and palatability traits. Objective measurements included Hunter Color, TBA, Kramer, and Instron values. Electrical stimulation reduced peak force but did not consistently improve sensory panel scores. Comminution method did not consistently affect any traits. Results suggested that subjective appearance was affected more by storage time than other treatments and that prerigor beef may be effectively utilized in restructured beef without affecting palatability traits.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1745-4557.1986.tb00769.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Breast abscess following central venous catheterization (1991)
    Springer
    Intensive care medicine 17 (1991), S. 123-124 
    Details
    ISSN: 1432-1238
    Keywords: Catheterization ; Central venous ; Complication ; Infection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We describe a case of late perforation of the right internal mammary vein by a central venous catheter inserted via the left subclavian vein. This resulted in extravasation of parenteral nutritional fluid and breast abscess formation. Delay in reaching the diagnosis was experienced in this case and in two cases previously reported. The clinical presentation was similar in all three cases with good early function of the catheters followed by symptoms of chest pain and signs of inflammation in the breast contralateral to the site of insertion of the central venous catheter. Confirmation of correct placement of the central venous catheter must be sought in any patient who develops these symptoms or signs so that the delay in diagnosis we experienced can be avoided. This may be obtained by a lateral or oblique chest radiograph or by contrast studies if preferable.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01691437
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Characterization of donor-directed antibody class in the post-transplant period using flow cytometry in renal transplantation (1994)
    Springer
    Transplant international 7 (1994), S. 182-189 
    Details
    ISSN: 1432-2277
    Keywords: Renal transplantation, post-transplant antibodies ; Antibodies, after renal transplantation ; Donor-direct antibodies ; Flow cytometry, renal transplantation, antibodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Over the past few years there has been increasing awareness of the importance of humoral mechanisms in the rejection of renal transplants. In this study we have monitored the development of antibodies directed against donor T and B lymphocytes using the sensitive flow cytometric technique. Forty-two cadaveric renal transplants were studied both before and for a maximum of 14 days after transplantation. Donor cells were separated from spleen on the day of transplantation and stored in liquid nitrogen until required. The dual colour flow cytometric assay was used to detect IgG or IgM directed againts donor T or B lymphocytes. Using AB sera as controls, results were expressed as relative median fluorescence (RMF) and then correlated with the clinical performance of the grafts. Significant associations were found between the incidence of donor-directed antibodies and the development of clinical rejection. The magnitude of the rise in antibody levels was also related to graft performance. In patients showing severe graft rejection, high levels of antibodies of the IgG class developed before the clinical diagnosis of rejection was made. The routine use of this test allows the prediction of impending severe rejection to be made and may have important implications for immunosuppressive therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00327085
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  • 4
    Electronic Resource
    Electronic Resource
    Renal epithelium: reversal of cytotoxic damage by addition of anti-thymocyte globulin (1991)
    Springer
    Transplant international 4 (1991), S. 210-214 
    Details
    ISSN: 1432-2277
    Keywords: Epithelium, renal, in vitro assay ; ATG rabbit, renal epithelium ; LAK cells, renal epithelium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A novel in vitro assay of renal epithelium tight junction function was used to assess the efficacy with which rabbit anti-thymocyte globulin (ATG) blocks epithelium damage mediated by lymphokine-activated killer (LAK) cells. It was found that LAK cells lysed renal epithelial cells poorly in standard chromium-release assays but that they caused a rapid, and almost total, reduction in trans-epithelium monolayer resistance, indicating tight junction failure and, hence, loss of tissue function. LAK cell-mediated cytolysis of the sensitive K562 cell line was completely blocked in the presence of ATG at a concentration of 200 μg/ml. Addition of ATG at this concentration to damaged renal cell monolayers in the presence of LAK cells allowed the trans-monolayer resistance to recover rapidly to levels approaching the values recorded before initial addition of LAK cells. On this basis it seems likely that the rapid restoration of renal function frequently observed after appropriate “rescue” therapy during episodes of acute rejection may reflect subtle changes in tissue function rather than recovery from widespread graft cell cytolysis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00649105
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  • 5
    Electronic Resource
    Electronic Resource
    Administration of ATG according to the absolute T lymphocyte count during therapy for steroid-resistant rejection (1993)
    Springer
    Transplant international 6 (1993), S. 18-21 
    Details
    ISSN: 1432-2277
    Keywords: Kidney transplantation, rejection, ATG ; ATG, rejection, kidney transplantation ; T lymphocyte count, ATG, kidney rejection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In renal transplantation, treatment of steroid-resistant rejection (SRR) with antithymocyte globulin (ATG) has been widely reported but over-immunosuppression remains a common problem. In the first ten patients (group 1) treated for SRR with rabbit ATG, three developed serious viral infections and two deaths occurred due to CMV pneumonitis. ATG was only omitted if thrombocytopenia or neutropenia occurred. In the next 17 patients (group 2) with SRR, ATG was administered according to the absolute T lymphocyte count. T lymphocytes were measured by flow cytometric analysis of CD3-labelled lymphocytes. ATG dosage was adjusted on a daily basis to keep the absolute T lymphocyte count under 50 cells/μl. Administration of ATG according to the absolute T lymphocyte count resulted in a significant reduction in the mean dose of ATG given to the group 2 patients (P〈0.001). A significant decrease in the incidence of serious viral infections (P=0.04) was achieved without reducing the ability of ATG to reverse the SRR (P=0.29) or increasing the number of grafts lost at 1 year in the group 2 patients (P=0.23).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00336633
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    Paper (German National Licenses)
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