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Digitale Medien

Distribution of epithelial membrane antigen in normal and abnormal endometrial tissue (1985)

MORSE, ANNE R. ; CURRAN, GEOFFREY J.

Oxford, UK : Blackwell Publishing Ltd

BJOG 92 (1985), S. 0

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ISSN: 1471-0528

Quelle: Blackwell Publishing Journal Backfiles 1879-2005

Thema: Medizin

Notizen: Summary. The distribution of epithelial membrane antigen (EMA) on normal and abnormal endometrial tissue was studied as a method for distinguishing atypical hyperplasia from adenocarcinoma. Histological sections from 47 patients (nine adenocarcinoma, ninc atypical hyperplasia, nine cystic hyperplasia, 19 normal endomctrium and one sircoma) were studied with an immunocytochemical alkaline phosphatase technique that derrionstratcd EMA. At adilution of 1:1000 the majority of normal tissue was negative whereas all the abnormal tissue stained positively. At a slightly higher dilution all adenocarcinomas expressed thc antigen although only a few of the hyperplastic lesions (16%) stained with the antibody. The value of this approach for automated screening is discusscd.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1111/j.1471-0528.1985.tb04877.x

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