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  • 1
    Electronic Resource
    Electronic Resource
    History of Electrocardiology (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of noninvasive electrocardiology 2 (1997), S. 0 
    Details
    ISSN: 1542-474X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1542-474X.1997.tb00205.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Sequential Alterations in Myocardial Lactate Metabolism, S-T Segments, and Left Ventricular Function During Angina Induced by Atrial Pacing (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of noninvasive electrocardiology 2 (1997), S. 0 
    Details
    ISSN: 1542-474X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Myocardial lactate metabolism was monitored before, during, and after a period of atrial pacing with a continuous automated sampling technic. The electrocardiogram was recorded, and left ventricular function was evaluated by relating left ventricular end-diastolic pressure to left ventricular stroke work. Seventeen of 21 patients with coronary artery disease experienced angina during pacing, and 13 of these showed lactate production by the myocardium during angina. The abnormalities in lactate metabolism developed early in the pacing period, along with S-T segment depression and impairment of left ventricular function, all of which usually occurred before the onset of pain. In the patients with angina, the mean lactate extraction was 14.1% during the control period and —15.1% during the pacing period. Abnormalities in myocardial lactate metabolism have been demonstrated with greater regularity during pacing-induced angina than during angina precipitated by exercise or isoproterenol. This investigation has demonstrated the sequences of changes in lactate metabolism during and after a period of angina and their relation to electrocardiographic and hemodynamic events.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1542-474X.1997.tb00206.x
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  • 3
    Electronic Resource
    Electronic Resource
    The Multicenter Research Group (2002)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of noninvasive electrocardiology 7 (2002), S. 0 
    Details
    ISSN: 1542-474X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1542-474X.2002.tb00174.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Adverse Prognosis of ST Depression on the Resting Electrocardiogram in Stable Patients Following Acute Myocardial Infarction (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of noninvasive electrocardiology 1 (1996), S. 0 
    Details
    ISSN: 1542-474X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: The aim of this study was to analyze the characteristics of stable patients with resting ST segment depression on the resting electrocardiogram (ECG) following an acute ischemic event (i.e., infarction or unstable angina) to better understand its association with subsequent cardiac death and nonfatal infarction. The recent Multicenter Study of Myocardial Ischemia (MSMI) demonstrated that the resting ST segment depression had an independent prognostic value.Methods: We studied clinical features, noninvasive test results and coronary arteriography findings in 99 patients with ST depression on the resting ECG and 837 patients without ST segment depression with respect to endpoints of cardiac death and hospitalization for acute myocardial infarction or unstable angina.Results: Our results showed that patients with resting ECG ST depression were significantly older with a higher incidence of hypertension, angina, claudication, and tobacco use. ST depression on the resting ECG correlated closely with ST segment depression on the 24-hour ambulatory ECG and the exercise ECG but not with redistribution on the thallium perfusion scan. Left ventricular diastolic pressure was higher and exercise duration less in patients with ST depression. Although not achieving statistical significance, patients with ST depression did show more extensive coronary disease and a lower ejection fraction.Conclusions: ECG ST depression was associated with cardiac death and nonfatal reinfarction over the follow-up period only in patients originally admitted with an acute infarction but not in patients hospitalized for unstable angina. The reason for this appears to be an association of ST depression with increased age, the presence of hypertension, the presence of more severe coronary disease, and more extensive myocardial damage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1542-474X.1996.tb00262.x
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  • 5
    Electronic Resource
    Electronic Resource
    The Clinical Significance of Somatic Pain Tolerance in Patients with Coronary Artery Disease (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of noninvasive electrocardiology 2 (1997), S. 0 
    Details
    ISSN: 1542-474X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Two hundred seventy-one patients with a recent acute coronary event underwent pain tolerance testing using the tourniquet test. Baseline ambulatory and exercise electrocardiography, and stress thallium scintigraphy were performed, and patients were followed prospectively for a mean of 33 ± 8 months for the occurrence of unstable angina, nonfatal myocardial infarction (Ml), or cardiac death.〈section xml:id="abs1-2"〉〈title type="main"〉ResultsPatients with lower tolerance to somatic pain were significantly older (P = 0.001), had more clinical angina (P = 0.04), and on multivariate analysis had poorer exercise tolerance (P = 0.002) than those with higher pain tolerance. Low and high pain tolerance patients demonstrated similar degrees of myocardial ischemia on noninvasive testing and had similar cardiac event rates (death, nonfatal Ml, or unstable angina) during the follow-up period.〈section xml:id="abs1-3"〉〈title type="main"〉ConclusionsDespite demonstrating a similar frequency of myocardial ischemia and similar prognosis as patients with high pain tolerance, individuals with low pain tolerance were more likely to experience clinical symptoms and functional impairment, providing evidence that individual differences in somatic pain tolerance influence the symptomatic expression of coronary disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1542-474X.1997.tb00198.x
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  • 6
    Electronic Resource
    Electronic Resource
    Steady-state analysis and evaluation of a new thermal sensor for surface measurements of tissue perfusion (1983)
    Springer
    Annals of biomedical engineering 11 (1983), S. 101-115 
    Details
    ISSN: 1573-9686
    Keywords: Thermal flow sensor ; Tissue perfusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract The steady-state response and operating characteristics of a new thermal sensor for surface measurements of local tissue perfusion have been analyzed theoretically and evaluated in vivo. The flow measurement system incorporates an electrically isolated thin-film thermal sensor, which is maintained at a fixed temperature by high frequency response electronic circuitry. The sensor rests on the tissue surface, and the power required to maintain a fixed probe to tissue temperature elevation is measured and related to tissue blood flow. A theoretical analysis of the steady-state probe response to flow changes was carried out employing the bio-heat-transfer equation and a solution based on Fourier series to describe the temperature distribution within the tissue domain. A comparison of steady-state theory to results obtained from initial experimental tests on the surface of the dog heart, over a perfusion range 0.51 to 2.00 ml/min/g, shows close agreement. The probe demonstrates good sensitivity to flow changes, provides stable and continuous measurements, and appears promising for both research and clinical applications.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02367494
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  • 7
    Electronic Resource
    Electronic Resource
    Measurement of regional myocardial perfusion using collimated miniature radiation detectors and the method of 133-Xenon washout (1983)
    Springer
    Annals of biomedical engineering 11 (1983), S. 479-494 
    Details
    ISSN: 1573-9686
    Keywords: Myocardial perfusion ; Cadmium telluride ; Xenon washout
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract A new approach to the measurement of local myocardial perfusion based on the application of highly-collimated miniature cadmium telluride radiation detectors to measure washout of 133-Xenon from well-defined tissue volumes is presented. Single-hole collimators with length/diameter ratios of 1 (L=4 mm, D=4 mm) and 4 (L=12 mm, D=3 mm) were employed as prototype designs. The probe field of view was characterized theoretically using a spherical model of the myocardium in conjunction with experimental point source response measurements for each collimator. Method evaluation using two medium resolution collimators (L/D=1) was effected by performing left main and circumflex coronary artery perfusion studies at controlled but variable flows in the dog heart. An excellent correlation (r〉0.99) between actual and estimated perfusion determined from 65 washout curves over the flow range 0.38 to 3.18 ml/min/gm was demonstrated. The ability to resolve regional flow differences was verified by measuring tracer washout from circumflex and left anterior descending regions of the myocardium, using two high resolution collimators (L/D=4), in a preparation where the left main coronary artery was cannulated and a snare was placed around the circumflex coronary artery to selectively reduce flow to that region.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00000007
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