Bibliothek

feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
  • 1
    ISSN: 1432-1459
    Schlagwort(e): E-UFA test ; Multiple sclerosis ; Retrobulbar optic neuritis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Nicht jeder Fall von Retrobulbärneuritis darf als erstes Symptom einer Multiplen Sklerose angesehen werden. Wir haben 41 Patienten mit Retrobulbärneuritis mit Hilfe des E-Ufa-Testes (Erythrocyte-unsaturated fatty acid test) untersucht. Diese Patienten wiesen keine anderen auf Multiple Sklerose verdächtigen Symptome auf. Der Test war positiv in 14 der Fälle (34,1%).
    Notizen: Summary Retrobulbar optic neuritis, though suspicious, is not always considered as a possible onset of MS. For this reason we submitted to the E-UFA (erythrocyte unsaturated fatty acid) test, 41 subjects who suffered from one or several episodes of retrobulbar optic neuritis with no other neurological signs. The test was positive in 14 subjects (34.1%).
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Acta neurochirurgica 12 (1964), S. 366-378 
    ISSN: 0942-0940
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Die Autoren besprechen die Begriffe „Wachheit“ und „Bewußtsein“ im Lichte der neueren psychopathologischen und neurophysiologischen Erkenntnisse. Sie vertreten die Ansicht, daß ein Zustand der Wachheit Voraussetzung für jegliche Bewußtseinstätigkeit ist, daß aber das Bewußtsein eine höhere Synthese jeglicher psychischer Aktivität darstellt, die Wahrnehmung, Verstand und Gefühl zusammenfaßt. Nach einer Beschreibung der wichtigsten klinischen Syndrome von Beeinträchtigungen von Bewußtsein und Wachheit besprechen die Autoren die besonderen Gesichtspunkte der Bewußtseinsstörungen bei endogenen Psychosen, vor allem bei der Schizophrenie.
    Kurzfassung: Résumé Les auteurs examinent les concepts de «vigilance» et de «conscience» à la lumière des toutes dernières découvertes en psychopathologie et neurophysiologie. Ils maintiennent qu'un état de vigilance est nécessairement préalable à une quelconque activité consciente, mais la conscience doit être considérée comme la plus haute synthèse de l'activité psychique toute entière dans laquelle s'intègrent perceptions, intelligence et émotions. Suivant une description des principaux syndromes cliniques où les fonctions de vigilance et la conscience sont particulièrement affectées, les auteurs examinent les aspects spéciaux de l'affaiblissement de la conscience dans les psychoses endogènes, surtout dans les schizophrénies.
    Notizen: Summary The authors discuss the concepts of “vigilance” and “consciousness” in the light of the latest findings of psychopathology and neurophysiology. They maintain that a state of vigilance is necessary before any conscious activity can take place, but consciousness should be considered as a higher synthesis of the whole psychic activity in which perceptions, intelligence and emotions are integrated. Following a description of the main clinical syndromes where the functions of vigilance and consciousness are particularly affected, the authors discuss the special aspects of the impairment of consciousness in endogenous psychoses, above all in schizophrenia.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Neuroradiology 28 (1986), S. 319-323 
    ISSN: 1432-1920
    Schlagwort(e): Magnetic resonance ; Multiple sclerosis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Magnetic Resonance Imaging was performed in more than 200 patients with clinical suspicion or knowledge of Multiple Sclerosis. One hundred and forty-seven (60 males and 87 females) had MR evidence of multiple sclerosis lesions. The MR signal of demyelinating plaques characteristically has prolonged T1 and T2 relaxation times and the T2-weighted spin-echo sequences are generally superior to the T1-weighted images because the lesions are better visualized as areas of increased signal intensity. MR is also able to detect plaques in the brainstem, cerebellum and within the cervical spinal cord. MR appears to be an important, non-invasive method for the diagnosis of Multiple Sclerosis and has proven to be diagnostically superior to CT, evoked potentials (EP) and CSF examination. In a selected group of 30 patients, with the whole battery of the relevant MS studies, MR was positive in 100%, CT in 33,3%, EP in 56% and CSF examination in 60%. In patients clinically presenting only with signs of spinal cord involvement or optic neuritis or when the clinical presentation is uncertain MR has proven to be a very useful diagnostic tool for diagnosis of MS by demonstrating unsuspected lesions in the cerebral hemispheres.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Journal of neurology 229 (1983), S. 55-60 
    ISSN: 1432-1459
    Schlagwort(e): Cerebrospinal fluid ; Isotachophoresis ; IgG ; Multiple sclerosis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Liquor und Serum von Patienten mit Multipler Sklerose und anderen neurologischen Erkrankungen wurden mittels Kapillar-Isotachophoresis (ITP) untersucht. Es wurde berechnet, welchen Anteil das IgG im Liquor, welcher langsam mit der ITP wanderte, ausmachte und wie seine Synthesegeschwindigkeit war. Bei den meisten Patienten mit Multipler Sklerose enthielt der Liquor einen erhöhten Anteil von langsam wandernden IgG, welches oligoclonalen Banden im hochalkalischen Bereich beim isoelectric focusing entsprach. Es wurde gefolgert, daß die Patienten mit Multipler Sklerose eine erhöhte intrathekale Synthese des langsamen IgG aufwiesen, wobei dies eng korrelierte mit dem Anteil der intrathekalen Liquor-IgG-Synthese, wie sie nach der Tourtellotteschen Formel errechnet werden kann.
    Notizen: Summary Cerebrospinal fluid (CSF) and serum samples from patients with multiple sclerosis and other neurological diseases were examined by capillary isotachophoresis (ITP). The percentage and the rate of synthesis of CSF IgG which migrated slowly with ITP were calculated. CSF specimens of most patients with multiple sclerosis contained increased percentages of slowly migrating IgG (slow IgG), corresponding to IgG oligoclonal bands in the “high-alkaline” region on isoelectric focusing. The patients with multiple sclerosis were found to have increased intrathecal synthesis of slow IgG, which correlated closely with the rate of intrathecal CNS IgG synthesis calculated by Tourtellotte's formula.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 5
    Digitale Medien
    Digitale Medien
    Springer
    Journal of neurology 237 (1990), S. 1-4 
    ISSN: 1432-1459
    Schlagwort(e): Multiple sclerosis ; T-cell subsets ; Naive T-cells ; Memory T-cells
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Circulating lymphocyte subpopulations defined by anti-CD45 and other more common T-cell-specific monoclonal antibodies were analysed in 77 patients with multiple sclerosis and 38 healthy controls. A selective decrease of CD4+ CD45+ cell percentages and absolute numbers in chronic-progressive patients was found; in 13 out of 26 patients this subpopulation was less than 11% CD4+ CD45+ cells. Similarly, the whole CD45+ cell subset, as well as CD45+ cells expressed as percentages of CD4+ cells, were significantly reduced in chronic-progressive multiple sclerosis. CD4+ CD45+ cells, commonly termed “inducer of suppression” T-lymphocytes, did not correlate with percentages or numbers of CD8+ cells. It is concluded that suppressor inducer T-cells act on the CD8+ subset function rather than reducing CD8+ cell numbers. Since CD4+ CD45+ cells represent an early stage of lymphocyte maturation (naive T-cells), an under-representation of this subpopulation in active multiple sclerosis might reflect an increased conversion of naive cells into memory cells. This concept may be relevant for a better understanding of the disease pathogenesis.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Neurological sciences 10 (1989), S. 199-202 
    ISSN: 1590-3478
    Schlagwort(e): Creutzfeldt-Jakob disease ; familial occurrence ; periodic synchronous discharges
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Sommario Sono presentati due casi famigliari italiani di malattia di Creutzfeldt-Jakob. Sono descritti il quadro clinico e il decorso e viene fatta una comparazione coi dati riportati su casi famigliari in altre nazioni e coi dati concernenti casi italiani sporadici.
    Notizen: Abstract Two familial Italian cases of Creutzfeldt-Jakob disease are reported. Clinical picture and life history are presented and compared: 1) with the findings in familial cases reported in other countries, 2) with the findings (age at onset, disease duration) in sporadic Italian cases.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 7
    ISSN: 1590-3478
    Schlagwort(e): Multimodal evoked potentials ; HIV infection
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Sommario Diciotto soggetti affetti da infezione da HIV in fase asintomatica sono stati studiati con Potenziali Evocati Multimodali per indagare l'eventuale coinvolgimento del S.N.C. Lo studio è stato ripetuto a 8–12 mesi di distanza. In 13 soggetti sono state evidenziate alterazioni neuropsicologiche confermate dal successivo controllo. I 5 soggetti risultati normali alla I registrazione si sono conservati tali alla registrazione successiva. I pazienti sono stati valutati anche con la WAIS. L'unico soggetto che ha presentato punteggi patologici era quello con maggiori alterazioni dei potenziali evocati. La metodica dei potenziali evocati si è mostrata capace di individuare il precoce interessamento del S.N.C. nell'infezione da HIV.
    Notizen: Abstract 18 subjects with symptomless HIV infection were investigated with multimodal evoked potentials for possible CNS involvement and again after an 8–12 month interval. 13 subjects showed neuropsychological changes, which were confirmed at the second examination. The 5 subjects found normal remained so at the second examination. On WAIS assessment the only patient to earn pathological scores was the one with the greatest evoked potentials changes. Thus the evoked potentials procedure proved capable of identifying early CNS involvement by HIV infection.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 8
    ISSN: 1590-3478
    Schlagwort(e): Plasma exchange ; lymphocytapheresis ; neuroimmunology ; cerebral evoked potentials ; multiple sclerosis
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Sommario Abbiamo valutato un trattamento a breve termine con linfocitoplasmaferesi in sei pazienti affetti da sclerosi multipla, con particolare attenzione ai riscontri elettrofisiologici ed immunologici. Prima e dopo il trattamento, in ogni paziente, sono stati valutati: i potenziali evocati visivi, somatosensoriali e uditivi del tronco, il flicker fusion test, il rapporto helper/suppressor dei T-linfociti circolanti, le immunoglobuline e gli immunocomplessi serici, il grado di invalidità secondo la scale di valutazione di Kurtzke. I tests adottati non hanno dimostrato variazioni significative a seguito del trattamento.
    Notizen: Abstract Short-term treatment with lymphocytoplasmapheresis was evaluated in 6 multiple sclerosis patients with special reference to the electrophysiological and immunological findings. Visual, somatosensory, brainstem auditory evoked potentials, flicker fusion test, helper/suppressor blood lymphocyte ratio, serum immunocomplexes and immunoglobulins and Kurtzke scores were evaluated in each patient before and after treatment. No statistically significant results were obtained.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 9
    ISSN: 1590-3478
    Schlagwort(e): Multiple sclerosis ; lymphocytapheresis ; plasma exchange
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Sommario Sei pazienti affetti da sclerosi multipla clinicamente definita sono stati trattati con linfocitoplasmaferesi per un anno. Prima del trattamento ed al termine di questo, sono stati valutati i potenziali evocati, il rapporto helper/suppressor dei linfociti ematici ed i dati clinici. I risultati sono stati confrontati con quelli di un gruppo di controllo di dieci pazienti affetti da sclerosi multipla. Il trattamento con linfocitoplasmaferesi non sembra modificare significativamente i dati clinici e di laboratorio del gruppo trattato.
    Notizen: Abstract 6 patients with definite MS underwent lymphocytoplasmapheresis for one year. Clinical data, evoked potential recordings and peripheral blood lymphocyte helper/suppressor ratio were assessed before and after the treatment and were compared with those of a control group of 10 multiple sclerosis patients. Lymphocytoplasmapheresis did not significantly modify clinical and laboratory findings compared with the control group.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 10
    Digitale Medien
    Digitale Medien
    Springer
    Neurological sciences 7 (1986), S. 343-348 
    ISSN: 1590-3478
    Schlagwort(e): Experimental epilepsy ; hyperbaric oxygen ; convulsions ; brain ; age ; mice ; pentylenetetrazole
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Sommario Due diversi metodi di indurre la convulsità sono utilizzati in un gruppo di topi albino Swiss di sesso maschile, di differenti età di vita: la esposizione all'ossigeno iperbarico e il trattamento con pentilentetrazolo. L'ossigeno iperbarico si dimostra in grado di costituire un modello valido di epilessia sperimentale con modalità dipendenti dall'età dell'animale. I topi più giovani presentano una latenza nel tempo di convulsività maggiore rispetto ai topi adulti, con un andamento della distribuzione dei tempi rispetto all'età che segue una curva di tipo iperbolico. Il pentilentetrazolo agisce come convulsivante con modalità identiche nei gruppi di animali di diverse età. Il modello di convulsività da ossigeno iperbarico ci sembra pertanto interessante non soltanto per lo studio della neurochimica del fenomeno convulsivo ma anche come possibile schema di indagine dei fenomeni biochimici e delle modificazioni di membrana che si verificano nel corso della maturazione e dell'invecchiamento cerebrale.
    Notizen: Abstract Two methods of inducing convulsions were used in male Swiss albino mice of different ages: exposure to hyperbaric oxygen and pentylenetetrazole treatment. Hyperbaric oxygen proved to be a valid model of experimental epilepsy with an age-dependent trend. The youngest mice presented a much longer convulsion latency time than the adult mice but the curve of distribution of latency time versus age showed progressively increasing sensitivity. Pentylenetetrazole induced convulsions, apart from the youngest subgroup, without variations by age. Hyperbaric oxygen convulsions provide an interesting model for the study not only of the neurochemistry of convulsions but also of the membrane changes that occur in the course of cerebral maturation and aging.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...