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  • 1
    Electronic Resource
    Electronic Resource
    An overview of plant diversity, land use and degradation in the Mediterranean region of Turkey (2002)
    Bingley : Emerald
    Environmental management and health 13 (2002), S. 442-449 
    Details
    ISSN: 0956-6163
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Medicine , Economics
    Notes: The Turkish Mediterranean region covers an area of 198.165km2, including ten states and a coastline of about 4,389km. The area has served as a womb for several civilisations. However, its rich plant diversity has been victimized through anthropomorphic pressures. Southwestern shores of Turkey are the main centre of coastal endemism in the Mediterranean basin. The flora in the region on the whole includes more than 700 endemics, out of which about 600 are East-Mediterranean elements. Out of the endemic taxa distributed in the region more than 40 are facing a threat of extirpation. The region embodies tertiary endemics as well, like Liquidamber orientalis, Eryngium thorifolium and Flueggea anatolica. High mountain zones abound in neoendemics. Although several protected areas have been created lately, demographic pressure, urbanisation, grazing, fires and erosion, are still posing a great threat to the plant diversity. This paper enlightens the impact of the aforementioned land degradation processes on the plant cover of this phytogeographical region in Turkey.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/09566160210441753
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  • 2
    Electronic Resource
    Electronic Resource
    The effect of oral vancomycin on chronic idiopathic constipation (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 9 (1995), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: A case study reporting the efficacy of oral vancomycin in a patient with chronic idiopathic constipation prompted this prospective trial of oral vancomycin in eight female patients (aged 21–61 years) with severe constipation resistant to the action of dietary fibre. Methods: The trial was divided into two consecutive 14-day periods. During the first period, each patient was given ispaghula, 3.5 g twice a day, and during the subsequent period they took 250 mg vancomycin t.d.s. per os, as well as the fibre supplement. During both periods they collected stools and recorded daily bowel symptoms (stool frequency, straining, stool consistency, subjective stool volume) in a diary. At the end of each period whole gut transit time and the breath hydrogen response to a standard meal, giving oro-caecal transit time, were measured along with gastrointestinal symptoms which were assessed on visual analogue scales. Results: Vancomycin caused a significant improvement in stool frequency, consistency, ease of defecation and the amount of stool patients felt they produced (all P 〈 0.05), but objective measures of daily stool weight and whole gut or oro-caecal transit time were not significantly different. Basal breath hydrogen levels were higher after vancomycin treatment in seven out of eight patients. One patient experienced a complete remission of symptoms when she took vancomycin and remains in remission after 14 months. This patient showed no elevation in basal breath hydrogen level. Conclusion: Although this study does not support the use of vancomycin for most patients with constipation, the results suggest that modification of the intraluminal flora may be of value in the treatment of the occasional case of idiopathic constipation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2036.1995.tb00353.x
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  • 3
    Electronic Resource
    Electronic Resource
    Fetal intestinal transplant as an accessory enteral segment (1997)
    Springer
    Pediatric surgery international 12 (1997), S. 367-369 
    Details
    ISSN: 1437-9813
    Keywords: Key words Fetal tissue transplantation ; Small intestinal transplantation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Fetal tissue transplantation has gathered considerable interest among researchers dealing with organ transplantation. A large number of studies concerning fetal intestinal transplantation have been published in the past 2 decades, almost all of them aiming to determine the feasibility of a properly functioning fetal transplant in continuity with the host's own enteral system. This study was designed to determine the absorptive capacity of the neogut in vivo, without anastomosing the transplant to the host's intestine, and to evaluate its use as an accessory enteral segment. Intestinal segments taken from Wistar albino fetuses were transplanted subcutaneously into the abdominal wall of 20 Sprague-Dawley rats. Immunosuppression was maintained by daily cyclosporin A (Cy A) 10 mg/kg injections s.c. and evaluated by determination of serum Cy A level and T-helper/T-suppressor cell ratio. The neogut was converted into a Thiry-Vella loop 2 weeks after transplantation. A test solution composed of 20% glucose and Trophamine was perfused via the stomas; glucose and amino acid absorption gradients were calculated. The gamma-glutamyl transferase (GGT) activity and mitotic index of the neogut were determined. Results were compared to those obtained from the host. There was no significant difference (P 〉 0.05) in glucose absorption between the neogut and the host tissue. Amino acid absorption and specific GGT activity were significantly less (P 〈 0.01) in the neogut. There was no significant difference (P 〉 0.05) between neogut and host intestine in mitotic index. Our data support the idea of using a transplanted fetal intestinal segment as an accessory feeding route.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003830050153
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  • 4
    Electronic Resource
    Electronic Resource
    Congenital granular-cell tumor of the gingiva (1998)
    Springer
    Pediatric surgery international 13 (1998), S. 594-596 
    Details
    ISSN: 1437-9813
    Keywords: Key words Congenital granular-cell tumor ; Myoblastoma ; Epulis ; Gingiva
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Congenital granular cell tumors of the gingiva (synonyms: congenital myoblastoma, congenital epulis) originate from the alveolar ridge in newborns. They are rare granular-cell tumors with benign histology. The main differential diagnosis is epignathus (oral teratoma). Early surgical excision is recommended due to a risk of airway obstruction and difficulty feeding.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003830050412
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  • 5
    Electronic Resource
    Electronic Resource
    The effect of polycythemic hyperviscosity on ischemic bowel necrosis (1996)
    Springer
    Pediatric surgery international 11 (1996), S. 547-549 
    Details
    ISSN: 1437-9813
    Keywords: Polycythemic hyperviscosity ; Necrotizing enterocolitis ; Neonatal spontaneous intestinal perforation Intestinal atresia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract It is known that polycythemia decreases the fluidity of the blood and impairs tissue perfusion due to red-cell sludging in the microcirculation. In this study, the effect of polycythemic hyperviscosity (PH) on bowel necrosis was evaluated in an experimental model of intestinal ischemia. Twenty-eight Wistar albino rats (90–170 g) were divided into two groups: group 1 was transfused to create hyperviscosity and then intestinal ischemia was produced (n = 16); in group 2 ischemia was produced without transfusion (n = 12). Intestinal ischemia was produced by clamping the superior mesenteric artery and the collateral arcades of the right colic artery for 30 min. Gross and histopathologic evaluations were performed by either immediate necropsy or relaparotomy 24 h later. Microscopic findings were graded from 0 to 3 according to the degree of ischemic changes. In group 1, 2 animals (12.5%) died before 24 h postoperatively; coagulation necrosis with grade 2 or 3 ischemic changes was observed in 10 animals (62.5%). In group 2 only a few hypertrophied Peyer's patches and capillary dilation were found, and all histopathologic changes were between grades 0 and 1. The difference between the histopathologic gradings of the two groups was significant (P 〈 0.001). It appears that in addition to reduced splanchnic blood flow, a secondary effect of PH is needed to induce ischemic coagulation necrosis. PH of the newborn must be considered a risk factor for necrotizing enterocolitis, so-called spontaneous intestinal perforations, and even intestinal atresia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00626063
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  • 6
    Electronic Resource
    Electronic Resource
    Fetal intestinal transplant as an accessory enteral segment (1997)
    Springer
    Pediatric surgery international 12 (1997), S. 367-369 
    Details
    ISSN: 1437-9813
    Keywords: Fetal tissue transplantation ; Small intestinal transplantation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Fetal tissue transplantation has gathered considerable interest among researchers dealing with organ transplantation. A large number of studies concerning fetal intestinal transplantation have been published in the past 2 decades, almost all of them aiming to determine the feasibility of a properly functioning fetal transplant in continuity with the host's own enteral system. This study was designed to determine the absorptive capacity of the neogut in vivo, without anastomosing the transplant to the host's intestine, and to evaluate its use as an accessory enteral segment. Intestinal segments taken from Wistar albino fetuses were transplanted subcutaneously into the abdominal wall of 20 Sprague-Dawley rats. Immunosuppression was maintained by daily cyclosporin A (Cy A) 10 mg/kg injections s.c. and evaluated by determination of serum Cy A level and T-helper/T-suppressor cell ratio. The neogut was converted into a Thiry-Vella loop 2 weeks after transplantation. A test solution composed of 20% glucose and Trophamine was perfused via the stomas; glucose and amino acid absorption gradients were calculated. The gamma-glutamyl transferase (GGT) activity and mitotic index of the neogut were determined. Results were compared to those obtained from the host. There was no significant difference (P 〉 0.05) in glucose absorption between the neogut and the host tissue. Amino acid absorption and specific GGT activity were significantly less (P 〈 0.01) in the neogut. There was no significant difference (P 〉 0.05) between neogut and host intestine in mitotic index. Our data support the idea of using a transplanted fetal intestinal segment as an accessory feeding route.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01076941
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  • 7
    Electronic Resource
    Electronic Resource
    Serum creatine kinase enzyme levels in the early diagnosis of spermatic cord torsion (1996)
    Springer
    Urological research 24 (1996), S. 329-331 
    Details
    ISSN: 1434-0879
    Keywords: Spermatic cord torsion ; Testis ; Creatine kinase ; Serum enzymes ; Children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Delay in the diagnosis of spermatic cord torsion (SCT) is still a significant cause of testicular loss in children. The aim of this experimental study was to assess the diagnostic value of serum creatine kinase (CK) in the early period following SCT. Forty male rats were assigned randomly into five similar groups: group A, control; group B, sham, right testis exposed, manipulated, and blood sampling at 6th h; group C, right SCT, blood sampling at 2nd h; group D, right SCT, blood sampling at 4th h; and group E, right SCT, blood sampling at 6th h. CK and its isoenzymes were measured in the sera of all animals. All testes were removed and examined histopathologically. Significant increases in serum CK levels compared to control and sham groups were observed at 4 and 6 h following SCT. The major increase in CK was observed in the CK-MM isoenzyme fraction. Histologic pictures showed varying degrees of edema, vascular congestion, and hemorrhage in the testicular tissue, but no necrosis in any of the study groups. These results showed that serum CK levels in rats in the early period following SCT increase significantly before necrosis of testicular tissue. This may be of value as a diagnostic test, to corroborate findings from clinical studies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00389788
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    Paper (German National Licenses)
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