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Regulation of cell division and malignant transformation (1988)

Bhargava, Pushpa M. ; Chandani, Sushil A.

Springer

Bioscience reports 8 (1988), S. 519-529

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ISSN: 1573-4935

Keywords: cell division ; malignancy ; transformation ; nutrient uptake ; resting state

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Chemistry and Pharmacology

Notes: Abstract The problem of regulation of cell division is essentially a problem of understanding regulation of transition from the resting state of a cell to the dividing state and vice versa. In malignancy the ability to revert back to a normal resting state is impaired. A model is presented which attempts to explain the control of the above transitions through control of uptake of essential nutrients by a transport-inhibitory protein. Experimental evidence in favour of the model is given.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01117330

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