Electronic Resource
Springer
Archives of environmental contamination and toxicology
8 (1979), S. 1-24
ISSN:
1432-0703
Source:
Springer Online Journal Archives 1860-2000
Topics:
Energy, Environment Protection, Nuclear Power Engineering
,
Medicine
Notes:
Abstract Metabolic fates of14C-toxaphene and two of the toxic components of toxaphene were studiedin vitro by using rat liver enzyme preparations. The enzyme systems involving toxaphene metabolism were characterized, using known cofactors and inhibitors to activate or inhibit individual enzyme reactions. The nature of toxaphene metabolites was studied through derivatization of metabolic products via chemical and enzymatic treatments. The results of thein vitro studies were compared to the metabolic patterns observedin vivo to ascertain the relative importance of each enzyme system in the total process of toxaphene degradation and excretion.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01055137
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