ISSN:
1433-2981
Keywords:
Erythrocyte membrane glycolipids
;
Thin layer chromatography
;
Cats
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Erythrocyte membrane glycolipids from blood type A and type B cats were examined by thin layer chromatography. The results indicate that the major erythrocyte membrane glycolipid of type A cats is NeuGc-NeuGc-Galactose-Glucose-Ceramide ([NeuGc]2GD3), where NeuAc represents N-glycolyl-neuraminic acid. In contrast, the major erythrocyte membrane glycolipid of type B cats is NeuAc-NeuAc-Galactose-Glucose-Ceramide ([NeuAc]2GD3), where NeuAc represents N-acetylneuraminic acid. These major erythrocyte membrane glycolipids may be the blood group antigens for type A and type B cats, respectively. All type A cats may have enzymes to synthesise erythrocyte membrane glycolipids with terminal NeuAc, whereas type B cats may lack the gene for N-acetylneuraminic acid hydroxylase, the enzyme that converts NeuAc into NeuGc.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00235369
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