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  • 1
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This study was designed to provide evidence for elucidating the mechanisms of neurokinin-3 receptor (NK3) in spinal pain modulation. First, colocalization of NK3 with the µ-opioid receptor (MOR1) was studied in the spinal dorsal horn of the rat. Confocal microscopy showed that about 44% of NK3-expressing neurons in laminae I and II were immunoreactive for MOR1, which corresponded to about 93% of the total population of MOR1-containing neurons in these laminae. Second, the relationship between NK3/MOR1-coexpressing neurons and those that express nitric oxide synthase (NOS) was examined by using a triple immunofluorescent staining method. About 37% of NK3-immunoreactive neurons were also NOS-immunoreactive, which constituted about 82% of NOS-immunoreacitve neurons in the superficial laminae. However, no triple-labelled neurons were detected. The present results indicate that there are two major distinct subpopulations of NK3-expressing neurons in the superficial dorsal horn, which suggests that the involvement of NK3 receptor in spinal nociception could be mediated by two distinct mechanisms, i.e. opioid and nitric oxide.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 594 (Aug. 2008), p. 7-14 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The objective of this research is to design and fabricate a general purpose 3D digitizer based ongrinding technique to completely acquire the geometry of an object, including its inner structure, andaccurately create its CAD model. How the 3D digitizer works is as follows. First a thin layer of anobject that is fixed in epoxy is removed by a grinder and the image of the cross section is taken by aCCD camera. The process is repeated until the images of all the cross sections of the object arecaptured. Then the images are stacked up by using software 3D-DOCTOR to obtain the 3D CADmodel.The accuracy of the 3D digitizer developed in the research was within 0.03 mm when measuring alength of 5.50 mm and the gauge R&R percentage was 25.99%. The performance shows that the 3Ddigitizer is promising for use in industry
    Type of Medium: Electronic Resource
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