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  • 1
    Digitale Medien
    Digitale Medien
    Clinical and Angiographic Characteristics of Coronary Artery Spasm (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 598 (1990), S. 0 
    Details
    ISSN: 1749-6632
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Allgemeine Naturwissenschaft
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1749-6632.1990.tb42351.x
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  • 2
    Digitale Medien
    Digitale Medien
    Vitamin C Prevents Radiation-Induced Endothelium-Dependent Vasomotor Dysfunction And De-Endothelialization By Inhibiting Oxidative Damage In The Rat (2001)
    Melbourne, Australia : Blackwell Science Pty
    Clinical and experimental pharmacology and physiology 28 (2001), S. 0 
    Details
    ISSN: 1440-1681
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: 1. The present study was undertaken to determine whether endothelial function or morphology was altered in aortic rings of rats after irradiation, to investigate the mechanism of radiation effects on the endothelium and to examine the effect of vitamin C treatment against radiation-induced damage of the endothelium.2. Female Sprague-Dawley rats were randomized into four groups (control, radiation, radiation + vitamin C, radiation + vitamin C + NG-nitro-L-arginine methyl ester (L-NAME); n = 10 for each group and n = 7 for the control group) and were irradiated with 10 Gy of 137Cs as a radiation source. Segments of the thoracic aorta were obtained and isometric tension, levels of 8-hydroxydeoxyguanosine (OH-dG) and immunohistochemical staining were measured.3. Irradiation significantly impaired the acetylcholine-induced vasodilation of aortic segments, an effect that could be prevented by pretreatment with vitamin C (500 mg/kg per day). This beneficial effect of vitamin C was abolished by the addition of L-NAME (100 μg/kg per day), an inhibitor of nitric oxide (NO) synthesis. Irradiation significantly increased the level of OH-dG in the aorta (1.02 ± 0.27 vs 2.61 ± 0.78 OH-dG/105 deoxyguanosine (dG) for control and irradiated tissues, respectively; P 〈 0.01), an increase that was prevented by vitamin C treatment (1.59 ± 0.23 OH-dG/105 dG; P 〈 0.01). Irradiation caused significant de-endothelialization (von Willebrand factor (vWF) staining was 93 ± 7 vs 100% in irradiated and control tissues, respectively; P 〈 0.05) and this was prevented by vitamin C treatment (vWF staining 98 ± 3%; P 〈 0.05).4. Radiation caused endothelial damage and impaired NO production through oxidative injury, resulting in a selective impairment of endothelial-dependent vasodilation that could be prevented by vitamin C, partly through anti-oxidant mechanisms.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1046/j.1440-1681.2001.03528.x
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  • 3
    Digitale Medien
    Digitale Medien
    Electrocardiographic Characteristics of Fasciculoventricular Pathways (2005)
    350 Main Street , Malden , MA 02148-5018 , USA and 9600 Garsington Road , Oxford OX4 2DQ , UK . : Blackwell Science Inc
    Pacing and clinical electrophysiology 28 (2005), S. 0 
    Details
    ISSN: 1540-8159
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Introduction: Fasciculoventricular (FV) pathways are rare variants of preexcitation, and their ECGs may be misinterpreted as Wolff-Parkinson-White syndrome with anteroseptal accessory pathways (WPW-AS). We analyzed the electrocardiographic characteristics of the patients with FV pathways to find out the different findings from WPW-AS. Methods and Results: Five patients with FV pathways and four patients with WPW-AS who underwent electrophysiologic studies were evaluated. Intervals and amplitudes of each wave and QRS morphologies were analyzed in standard 12-lead ECGs of these patients by two independent cardiologists without the information of the electrophysiologic findings. PR intervals were longer in FV pathways (122 ± 11.0 vs 83 ± 21 ms, FV pathways vs WPW-AS, P = 0.017). In lead V1, narrower width of R waves (25 ± 6 vs 45 ± 13 ms, P = 0.037) and smaller amplitude of S waves (12.8 ± 8.3 vs 26.6 ± 7.4 mm, P = 0.037) were observed in FV pathways. The polarity of delta waves in V1 was flat or negative in contrast with the cases of WPW-AS in which the polarity was positive. Three of five patients had notching in the descending limb of S waves in V1, which was not observed in WPW-AS. Conclusion: FV pathways have different ECG characteristics from WPW-AS in PR interval and morphology of QRS complexes in lead V1 of the standard 12-lead ECG.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1540-8159.2005.09371.x
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  • 4
    Digitale Medien
    Digitale Medien
    Differential Diagnosis of Slow/Slow Atrioventricular Nodal Reentrant Tachycardia from Atrioventricular Reentrant Tachycardia Using Concealed Posteroseptal Accessory Pathway by 12-Lead Electrocardiography (2003)
    350 Main Street , Malden , MA 02148-5018 , U.S.A . : Blackwell Publishing
    Pacing and clinical electrophysiology 26 (2003), S. 0 
    Details
    ISSN: 1540-8159
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Slow pathways are used as both antegrade and retrograde conduction pathway in slow/slow atrioventricular nodal reentrant tachycardia (SS-AVNRT), and patients with SS-AVNRT have tachycardia ECGs mimicking atrioventricular reentrant tachycardia using concealed posteroseptal accessory pathway (PS-AVRT). Therefore, SS-AVNRT can be misdiagnosed as PS-AVRT, and the differential diagnosis is clinically important. Standard 12-lead ECGs during tachycardia were analyzed in patients with SS-AVNRT (n = 10) and PS-AVRT (n = 10). All these patients were diagnosed by electrophysiological study and underwent successful catheter ablation. Differences of the RP' intervals (dRP') between V1 and the inferior leads were evaluated. SS-AVNRT had significantly longer RP' intervals measured in V1 (167 ± 25.2 vs 137 ± 26.8 ms, SS-AVNRT vs PS-AVRT, respectively, P = 0.02), longer dRP' between V1 and II (dRP'[V1-II], 37 ± 14 vs 17 ± 6.7 ms, P = 0.0007), longer dRP'[V1-III] (39 ± 14 vs 17 ± 9.9 ms, P = 0.0011), and longer dRP'[V1-aVF] (39 ± 13 vs 20 ± 9.5 ms, P = 0.0008). The following criteria were suggested for differential diagnosis of SS-AVNRT from PS-AVRT: dRP'[V1-II] 〉25 ms (sensitivity and specificity: 80% and 100%, respectively), dRP'[V1-III] 〉23 ms (90% and 90%), dRP'[V1-aVF] 〉30 ms (90% and 90%). Differences of the RP' intervals between V1 and the inferior leads in the tachycardia ECGs were useful for differential diagnosis of SS-AVNRT from PS-AVRT. (PACE 2003; 26:2296–2300)
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1540-8159.2003.00362.x
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  • 5
    Digitale Medien
    Digitale Medien
    Takayasu arteritis in Korea: Clinical and angiographic features (1992)
    Springer
    Heart and vessels 7 (1992), S. 55-59 
    Details
    ISSN: 1615-2573
    Schlagwort(e): Takayasu arteritis ; Aortography ; Coronary angiography
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Clinical and angiographic features of Takayasu arteritis were investigated in 129 Korean patients. This disease affects females more frequently than males, in a ratio of 6.6 to 1. Of the total number of patients, 51 were in the third decade, 27 in the fourth decade, and 23 in the second decade. Common clinical symptoms were headache (60%), exertional dyspnea (42%), dizziness (36%), and malaise or weakness (34%). Takayasu arteritis affected the abdominal aorta (46%) and descending thoracic aorta (37%) more frequently than the ascending aorta (1%) and aortic arch (2%) According to Ueno's classification based on aortographic findings, the 129 patients were divided into type I (37), type II (25), and type III (67). Among the 48 patients who had coronary angiography, 11 (23%) showed coronary arterial involvement. Because the clinical features are determined by the extent and severity of the specific artery involved in the occlusive phase of the disease, total aortography including coronary angiography is very important in the initial evaluation of Takayasu arteritis.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01744545
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